› 1b4r

Solution NMR

PKD DOMAIN 1 FROM HUMAN POLYCYSTEIN-1

Released:
DOI: 10.2210/pdb1b4r/pdb
PDB entry 1b4r coloured by chain, ensemble of 20 models, front view.
PDB entry 1b4r coloured by chain, ensemble of 20 models, side view.
PDB entry 1b4r coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
The structure of a PKD domain from polycystin-1: implications for polycystic kidney disease.
Bycroft M, Bateman A, Clarke J, Hamill SJ, Sandford R, Thomas RL, Chothia C
EMBO J 18 297-305 (1999)
PMID: 9889186

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161355 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Polycystin-1 Chain: A
Molecule details ›
Chain: A
Length: 80 amino acids
Theoretical weight: 7.96 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P98161 (Residues: 275-354; Coverage: 2%)
Gene name: PKD1
Sequence domains: PKD domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: SA
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

26 review citations

The C-type lectin-like domain superfamily.
Zelensky et al. (2005)
25 more

10 mentions without citation

Structural biology of TRP channels.
Hellmich et al. (2014)
9 more