› 1agt

Solution NMR

SOLUTION STRUCTURE OF THE POTASSIUM CHANNEL INHIBITOR AGITOXIN 2: CALIPER FOR PROBING CHANNEL GEOMETRY

Released:
DOI: 10.2210/pdb1agt/pdb
PDB entry 1agt coloured by chain, ensemble of 17 models, front view.
PDB entry 1agt coloured by chain, ensemble of 17 models, side view.
PDB entry 1agt coloured by chain, ensemble of 17 models, top view.
Source organism: Leiurus quinquestriatus hebraeus
Primary publication:
Solution structure of the potassium channel inhibitor agitoxin 2: caliper for probing channel geometry.
Krezel AM, Kasibhatla C, Hidalgo P, MacKinnon R, Wagner G
Protein Sci. 4 1478-89 (1995)
PMID: 8520473

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155438 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Potassium channel toxin alpha-KTx 3.2 Chain: A
Molecule details ›
Chain: A
Length: 38 amino acids
Theoretical weight: 4.1 KDa
Source organism: Leiurus quinquestriatus hebraeus
Expression system: Escherichia coli
UniProt:
  • Canonical: P46111 (Residues: 1-38; Coverage: 100%)
Sequence domains: Scorpion short toxin, BmKK2

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Escherichia coli

Quick links

Citations

8 review citations

The charybdotoxin family of K+ channel-blocking peptides.
Miller C. (1995)
7 more

19 mentions without citation

Computational methods of studying the binding of toxins from venomous animals to biological ion channels: theory and applications.
Gordon et al. (2013)
18 more