› 1a9v

Solution NMR

TERTIARY STRUCTURE OF THE MAJOR HOUSE DUST MITE ALLERGEN DER P 2, NMR, 10 STRUCTURES

Released:
DOI: 10.2210/pdb1a9v/pdb
PDB entry 1a9v coloured by chain, ensemble of 10 models, front view.
PDB entry 1a9v coloured by chain, ensemble of 10 models, side view.
PDB entry 1a9v coloured by chain, ensemble of 10 models, top view.
Source organism: Dermatophagoides pteronyssinus
Primary publication:
Tertiary structure of the major house dust mite allergen Der p 2: sequential and structural homologies.
Mueller GA, Benjamin DC, Rule GS
Biochemistry 37 12707-14 (1998)
PMID: 9737847

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155908 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mite group 2 allergen Der p 2 Chain: A
Molecule details ›
Chain: A
Length: 129 amino acids
Theoretical weight: 14.11 KDa
Source organism: Dermatophagoides pteronyssinus
Expression system: Escherichia coli
UniProt:
  • Canonical: P49278 (Residues: 18-146; Coverage: 100%)
Gene name: DERP2
Sequence domains: ML domain
Structure domains: Immunoglobulin-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY, SIMULATED ANNEAL
Expression system: Escherichia coli

Quick links

Citations

16 review citations

The alliance of genes and environment in asthma and allergy.
Cookson W. (1999)
15 more

5 mentions without citation

Relevant B cell epitopes in allergic disease.
Pomés A. (2010)
4 more