› 1a8a

X-ray diffraction
1.9Å resolution

RAT ANNEXIN V COMPLEXED WITH GLYCEROPHOSPHOSERINE

Released:
DOI: 10.2210/pdb1a8a/pdb
PDB entry 1a8a coloured by chain, front view.
PDB entry 1a8a coloured by chain, side view.
PDB entry 1a8a coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Ca(2+)-bridging mechanism and phospholipid head group recognition in the membrane-binding protein annexin V.
Swairjo MA, Concha NO, Kaetzel MA, Dedman JR, Seaton BA
Nat Struct Biol 2 968-74 (1995)
PMID: 7583670

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147017 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Annexin A5 Chain: A
Molecule details ›
Chain: A
Length: 319 amino acids
Theoretical weight: 35.68 KDa
Source organism: Rattus norvegicus
UniProt:
  • Canonical: P14668 (Residues: 2-319; Coverage: 100%)
Gene names: Anx5, Anxa5
Sequence domains: Annexin
Structure domains: Annexin

Ligands and Environments

2 bound ligands:
Ligand CA 10 x CA
Ligand GSE 1 x GSE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: R3
Unit cell:
a: 157.27Å b: 157.27Å c: 37.45Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.201 0.201 not available

Quick links

Citations

35 review citations

Annexins: linking Ca2+ signalling to membrane dynamics.
Gerke et al. (2005)
34 more

12 mentions without citation

Phosphatidylserine receptors: enhancers of enveloped virus entry and infection.
Moller-Tank et al. (2014)
11 more