Function and Biology Details
Reaction catalysed:
Inactivates bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a carboxyamide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred (1).
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
homo hexamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cysteine proteinase 1, mitochondrial
Molecule details ›
Chain: A
Length: 471 amino acids
Theoretical weight: 54.05 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Peptidase C1-like family
Structure domains: Cysteine proteinases
Length: 471 amino acids
Theoretical weight: 54.05 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q01532 (Residues: 30-483; Coverage: 94%)
Sequence domains: Peptidase C1-like family
Structure domains: Cysteine proteinases
