triangle PDBeMotif: 4r2g  
  coner Sequences coner   coner 3D motifs coner   coner Ligand environment coner   coner Ligand bonds coner
   
coner
   Search  |  PDB header search  |  Upload PDB file  |  Molecule binding  |  Pair bonds  |  Motif binding  |  3D environment  |  Motif inclusion  
coner
AstexViewer TM
Download original PDB file
Download xml file
Download structure factors file
Classification immune system    | release date: Mon, Aug 11, 2014
Title crystal structure of pgt124 fab bound to hiv-1 jrcsf gp120 c cd4
Authors F.GARCES, I.A.WILSON
Method X-RAY DIFFRACTION (resolution: 3.28Å)
PDBe Citation   
Small molecules:    search BMA BMA binding statistics BMA   search NAG NAG binding statistics NAG   search MAN MAN binding statistics MAN   search GOL GOL binding statistics GOL   search CL CL binding statistics CL
Modified residues:  search THR THR binding statistics THR search ASN ASN binding statistics ASN
Ligand bond colours:   *  covalent   *  ionic   *  hydrogen   *  electrostatic   *  van-der-waals   *  plane-atom   *  plane-plane   *  undefined  - Click here to show 5Å bonds
Chains E,O,A,K sequence:
DFNMWKNNMVEQMQEDVINLWDQSLKPCVKLTGGSVITQACPKVSFEPIPIHYCAPAGFAILKCNNKTFNGKGQCKNVST
VQCTHGIRPVVSTQLLLNGSLAEEKVVIRSDNFTDNAKTIIVQLNESVKINCTRPSNNTRPGEIIGDIRQAHCNISRAQW
NNTLKQIVEKLREQFNNKTIVFTHSSGGDPEIVMHSFNCGGEFFYCNSTQLFNSTWNDTEKSSGTEGNDTIILPCRIKQI
INMWQEVGKAMYAPPIKGQIRCSSNITGLLLTRDGGKNESEIEIFRPGGGDMRDNWRSELYKYKVVKIE
Chains F,B,H,L sequence:
MKKVVLGKKGDTVELTCTASQKKSIQFHWKNSNQIKILGNQGSFLTKGPSKLNDRADSRRSLWDQGNFPLIIKNLKIEDS
DTYICEVEDQKEEVQLLVFGLTANSDTHLLQGQSLTLTLESPPGSSPSVQCRSPRGKNIQGGKTLSVSQLELQDSGTWTC
TVLQNQKKVEFKIDIVVLAFQKAS
Chains P,C,I,M sequence:
SYVSPLSVALGETARISCGRQALGSRAVQWYQHKPGQAPILLIYNNQDRPSGIPERFSGTPDINFGTTATLTISGVEVGD
EADYYCHMWDSRSGFSWSFGGATRLTVLSQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAG
VETTTPSKQSNNKYAASSYLSLTPEQWKSHKSYSCQVTHEGSTVEKTVAPTECS
Chains Q,D,J,N sequence:
QVQLQESGPGLVRPSETLSVTCIVSGGSISNYYWTWIRQSPGKGLEWIGYISDRETTTYNPSLNSRAVISRDTSKNQLSL
QLRSVTTADTAIYFCATARRGQRIYGVVSFGEFFYYYYMDVWGKGTAVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCL
VKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCD
Residue colours:  hydrophilic   hydrophobic   intermediate 
Assembly 1     View the assembly/model: ( JMolViewer Download PDB file RasMol script viewer AstexViewer™@MSD-EBI )
Motif search   chain:    Sequence numbers: 
   Using:   φ/ψ    residues code    secondary structures   
 coordinates of:  Cαs Side-chain
 
      View the fragment: rasmol script JMol viewer
chain E : SURFACE PROTEIN GP160
member of: GENE3D:searchG3DSA_2.170.40.20PFAM:searchPF00516SUPERFAMILY:searchSSF56502UniProt:searchP20871
JMol viewer RasMol script viewer  CL 519E  ..                                                                                                                                          ..     *                                                                                                             * *                                               
JMol viewer RasMol script viewer  NAG 518E  ..                                                                                       *         *                                        ..     |                                                                                                             | |   *                                           
JMol viewer RasMol script viewer  NAG 517E  ..                                                                                       |         |                                        ..     |                                                            *                 *                              | |   |                                           
JMol viewer RasMol script viewer  NAG 516E  ..                                                                                       |         |                                        ..     |                                                            *  *              |                              | |   |                                           
JMol viewer RasMol script viewer  NAG 515E  ..                                                                                       |         |                                        ..     |                                                         * **  |              |     *                        | |   |                                           
JMol viewer RasMol script viewer  NAG 514E  ..                                                                                       |         |                                        ..     |       *   *                                             | ||  |           ***|     |                        | |   |                                           
JMol viewer RasMol script viewer  NAG 513E  ..                                                                                       |         |                                *       ..     |       |   |                                             | ||  |           ||||     |                        | |   |                                           
JMol viewer RasMol script viewer  NAG 512E  ..                                                                                       |         |             *  *               |       ..     |       |   |                                             | ||  |           ||||     |                        | |   |                                           
JMol viewer RasMol script viewer  NAG 511E  ..                                                                                       | *      **             |  |               |       ..     |       |   |                                             | ||  |           ||||     |                        | | **|                                           
JMol viewer RasMol script viewer  MAN 508E  ..                                                                                       | |      ||             |  |               |       ..     |       |   |                                             | ||  |           ||||     |                        | | |||                                           
JMol viewer RasMol script viewer  NAG 502E  ..                                                                                       | |      ||             |  |               |       ..     *       |   |                                             | ||  |           ||||     |                        | | |||                                           
JMol viewer RasMol script viewer  NAG 501E  ..                                                                                       | |      ||             |  |               *       ..     |  * *  |   |                                             | ||  |           ||||   * |                        | | |||                                           
sec str:  ....hhhhhhhhhhhhhhhhhhhhhhh...eee...........................eeeeee.............eeee.............eee.........eee..........eeeeeeeeeeeeeee..............eeeeehhhhhhhhhhhhhhhhhhh...eeee......hhhhhheeeee..eeeee.hhhhh.eee.....ee......eeeeeeeee.eee......eee........eeeeeeeeeeeeee........eeeeee...hhhhhhhhhhh..eeee.
sequence :  ..DFNMWKNNMVEQMQEDVINLWDQSLKPCVKLTGGSVITQACPKVSFEPIPIHYCAPAGFAILKCNNKTFNGKGQCKNVSTVQCTHGIRPVVSTQLLLNGSLAEEKVVIRSDNFTDNAKTIIVQLNESVKINCTRPSNN..IIGDIRQAHCNISRAQWNNTLKQIVEKLREQFNNKTIVFTHSSGGDPEIVMHSFNCGGEFFYCNSTQLFNSTWNDTEKSSGTEGNDTIILPCRIKQIINMWQEVGKAMYAPPIKGQIRCSSNITGLLLTRDGGKNESEIEIFRPGGGDMRDNWRSELYKYKVVKI
seq num:  ..92        102       112       122       205       215       225       235       245       255       265       275       285       295     ..322       332       342       352       363       373       383       393       403       417       427       437       447       457       467       477       487  
search RasMol script viewer Motif-ligand binding stats  ASN_GLYCOSYLATION ..      | |         |  | | |       || | |                |  |    | ^***| ||   ^***       | | |  || ^*** |        ^***  |      ^***| ^***  ^*..          ^***   ^***|           ^***     |  | |  |            ^***||^***^***| || | ^***                          |    | ^***    |    ^*** |       ||| ||  ||        
search RasMol script viewer Motif-ligand binding stats  PKC_PHOSPHO_SITE ..      | |         |  | ^**       || | |                |  |    | |   | ||    |         | | |  ||  ||  |        |  |  |        ^**         ..                   ^**                    |  | |  |             || ||  |  |^** || |  |                            |    |    |    |      |  |       ||| ||  ||        
search RasMol script viewer Motif-ligand binding stats  CK2_PHOSPHO_SITE ..      | |         |  |           || | |                |  |    | |   | ||    |         | | |  ||  |^***        |  |  |                    ..                                          ^*** |  |             || ||  ^***    ^***  |                            |    |    |    |      ^***       ||| ||  ||        
search RasMol script viewer Motif-ligand binding stats  MYRISTYL ..      | |         |  |           ^*****                |  |    | |   | |^*****         | | |  ||  |            |  |  |                    ..                                               |  |             || ||           ^*****                            ^*****    ^*****                 ||| ||  ||        
search RasMol script viewer Motif-ligand binding stats  alphabetamotif ..      | |         |  |            | |                  |  |    | |   | |               | | |  ||  |            |  |  |                    ..                                               |  |             *****           | |                                                                |*********        
search RasMol script viewer Motif-ligand binding stats  asxturn ..      ***         |  |            | |                  |  |    | |   | |               | | |  ||  |            |  |  |                    ..                                               |  |             || ||           | |                                                                *** ||  |         
search RasMol script viewer Motif-ligand binding stats  betaturn ..                  |  |            | |                  ****    | |   | |               | | |  ||  |            |  ****                    ..                                               |  |             *****           | |                                                                 ********         
search RasMol script viewer Motif-ligand binding stats  gammaturn ..                  |  |            | |                  |  |    | |   | |               *** |  ||  |            |  |  |                    ..                                               |  |                             | |                                                                                  
search RasMol script viewer Motif-ligand binding stats  nest ..                  |  |            ***                  |  |    | |   ***                   |  ||  |            |  |  |                    ..                                               |  |                             ***                                                                                  
search RasMol script viewer Motif-ligand binding stats  niche ..                  ****                                 ****    ***                         ********            *******                    ..                                               ****                                                                                                                  

chain F : T-CELL SURFACE GLYCOPROTEIN CD4
member of: GENE3D:searchG3DSA_2.60.40.10PANTHER:searchPTHR11422/searchPTHR11422_SF0PFAM:searchPF05790/searchPF07686/searchPF09191PROSITE PROFILES:searchPS50835, SMART:searchSM00406/searchSM00409SUPERFAMILY:searchSSF48726UniProt:searchP01730
JMol viewer RasMol script viewer  NAG 512E  ..                                                                                                                                                                               
sec str:  ...eeeeee....eee...........eeeee....eeeeee..eeee........ee.hhhhhhhh...eee...hhhhheeeeeee...eeeeeeeeeeee.............eeeee.......eeeee.....eeee..eee.........eeeeeeeee..eeeeeeeee.
sequence :  ..KKVVLGKKGDTVELTCTASQKKSIQFHWKNSNQIKILGNQGSFLTKGPSKLNDRADSRRSLWDQGNFPLIIKNLKIEDSDTYICEVEDQKEEVQLLVFGLTANSDTHLLQGQSLTLTLESPPGSSPSVQCRSPRGKNIQGGKTLSVSQLELQDSGTWTCTVLQNQKKVEFKIDIV
seq num:  ..1         11        21        31        41        51        61        71        81        91        101       111       121       131       141       151       161       171  
search RasMol script viewer Motif-ligand binding stats  PKC_PHOSPHO_SITE ..    |  |         |^**        | |||   |  | |     | || || ^**| ||| |        ||  |  |                |  | |||| | |||  |    | ||   |   ^** |   |  |   |  ||  ||    |               
search RasMol script viewer Motif-ligand binding stats  CK2_PHOSPHO_SITE ..    |  |         | |         | |||   |  | |     | || ||   |^***| |        ||  |  |                |  | |||| | |||  |    | ||   |     | |   |  |   ^***|  ||    |               
search RasMol script viewer Motif-ligand binding stats  TYR_PHOSPHO_SITE ..    |  |         | |         | |||   |  | |     | || ||   |  | | |        *******^                |  | |||| | |||  |    | ||   |     | |   |  |       |  ||    |               
search RasMol script viewer Motif-ligand binding stats  MYRISTYL ..    |  |         | |         | |||   ^*****     | || ||   |  | | |         |  |                   ^*****||| | ^*****    | ^*****     | |   |  |       |  |^*****               
search RasMol script viewer Motif-ligand binding stats  AMIDATION ..    ^***         | |         | |||      | |     | || ||   |  | | |         |  |                      | |||| |  ||  |    |  |         | |   |  |       |  |                     
search RasMol script viewer Motif-ligand binding stats  betabulgeloop ..                 | |         *****      | |     | || ||   |  | | |         |  |                      | |||| |  ||  |    |  |         | |   |  |       |  |                     
search RasMol script viewer Motif-ligand binding stats  betaturn ..                 | |         ****|      | |     | ****|   **** | |         ****                      | |||| ****|  |    |  |         | |   |  |       |  |                     
search RasMol script viewer Motif-ligand binding stats  nest ..                 | |           ***      | |     | ||  |        ***         |  |                      ****** |  ||  |    |  |         ***   |  |       |  |                     
search RasMol script viewer Motif-ligand binding stats  niche ..                 ***                    ***     | |****                    ****                        | |  ********    ****               ****       ****                     
search RasMol script viewer Motif-ligand binding stats  stturn ..                                                ***                                                    ***                                                                     

chain P : PGT124 LIGHT CHAIN
JMol viewer RasMol script viewer  MAN 510E  ..                                             *               *                                                                                                                                                    
JMol viewer RasMol script viewer  MAN 509E  ..                                           ***              *|                                                                                                                                                    
JMol viewer RasMol script viewer  MAN 508E  ..                       *                   |||              ||                                                                                                                                                    
sec str:  .....eeeee....eeee...........eeeee......eeee.............ee...........eeee...hhhhh.eeeee..............eeeeeee..............hhhhhhh..eeeeeeeeee.....eeee..........eee...ee.....eeeeeeeeehhhhhhh...eeeeee....eeeeee...
sequence :  ..YVSPLSVALGETARISCGRQALGSRAVQWYQHKPGQAPILLIYNNQDRPSGIPERFSGTPDINFGTTATLTISGVEVGDEADYYCHMWDSRSGFSWSFGGATRLTVLSQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHKSYSCQVTHEGSTVEKTVAPT
seq num:  ..5         17        27        37        47        57        66        74        84        94        101       111       121       131       141       151       161       171       181       191       201       
search RasMol script viewer Motif-ligand binding stats  PKC_PHOSPHO_SITE ..           ^**                          ||      |  ||  |    | | ||   |  || || ||                                         |  |  | |                   | |    | ||   |     | |             | ^** | |   |  |  |      
search RasMol script viewer Motif-ligand binding stats  CK2_PHOSPHO_SITE ..                                        ||      |  ||  |    | | ||   |  ^***| ||                                         ^***  | |                   | |    | ||   |     | |             |  |  | |   |  ^***      
search RasMol script viewer Motif-ligand binding stats  MYRISTYL ..                                        ||      |  ||  |    | | ^*****   ^*****|                                            |  | |                   | |    | ^*****     | |             |  |  | |   |            
search RasMol script viewer Motif-ligand binding stats  IG_MHC ..                                        ||      |  ||  |    | |  |          |  |                                            |  | |                   | |    |  |         | |             |  |  **^****            
search RasMol script viewer Motif-ligand binding stats  betabulge ..                                        **      |  ||  |    | |  |          |  |                                            |  | |                   | |    |  |         | |             |  |                     
search RasMol script viewer Motif-ligand binding stats  betaturn ..                                                |  ||  |    | |  |          |  |                                            **** |                   | |    |  |         | |             |  |                     
search RasMol script viewer Motif-ligand binding stats  nest ..                                                |  ||  |    | |  |          |  |                                               ***                   ***    |  |         ***             |  |                     
search RasMol script viewer Motif-ligand binding stats  niche ..                                                ********    ******          ****                                                                            ****                         ****                     

chain Q : PGT124 HEAVY CHAIN
JMol viewer RasMol script viewer  NAG 517E  ..                                                                                                                                                  ..                                                                                  
JMol viewer RasMol script viewer  MAN 509E  ..                                                                                                     *                                            ..                                                                                  
JMol viewer RasMol script viewer  MAN 508E  ..                                                                                                     *                                            ..                                                                                  
JMol viewer RasMol script viewer  BMA 503E  ..                                                                                                     |*                                           ..                                                                                  
JMol viewer RasMol script viewer  NAG 502E  ..                                                                                                     |* ***                                       ..                                                                                  
JMol viewer RasMol script viewer  NAG 501E  ..                                                                                                     || |||                                       ..                                                                                  
JMol viewer RasMol script viewer  MAN 504E  ..                                                                                                     || |||                                       ..                                                                                  
JMol viewer RasMol script viewer  MAN 506E  ..                                                                                                    *|| |||                                       ..                                                                                  
sec str:  ...eeeee...ee.....eeeeeeee..hhhhheeeeeee.....eeeeeee.....eee.hhhh..eeeeee....eeeeee...hhhhheeeeeeeeeeeeee..hhhhh.eeeeee.......eeeee........eeeee.........eeeeeeeeeee.....eeee........eee...ee.....eeeeeeeeee.hhh....eeeeeee....eeeeeee..
sequence :  ..VQLQESGPGLVRPSETLSVTCIVSGGSISNYYWTWIRQSPGKGLEWIGYISDRETTTYNPSLNSRAVISRDTSKNQLSLQLRSVTTADTAIYFCATARRGQRIYGVVSFGEFFYYYYMDVWGKGTAVTVSSASTKGPSVFPLAPSS..SGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP
seq num:  ..2         12        22        32        42        52        62        72        82        89        99        100       103       113       141   ..150       160       170       180       190       200       210       220         
search RasMol script viewer Motif-ligand binding stats  PKC_PHOSPHO_SITE ..                        |  | ||       |  |      | ^**||   | || | |     ^** |    |  ||| ||      ^**        |||||            |    |   ^**         ^*.. | |  |                  |    |        | |||          |  |    | |   |  | |  |     
search RasMol script viewer Motif-ligand binding stats  CK2_PHOSPHO_SITE ..                        |  | ||       |  |      | ^***|   | || | |       | |    |  |^***|                 |^***            |    |                 .. | |  |                  |    |        | |||          |  |    | |   |  | ^***     
search RasMol script viewer Motif-ligand binding stats  TYR_PHOSPHO_SITE ..                        |  | ||       |  *******^ | | |   | || | |       | |    |  | |  |                 | |||            |    |                 .. | |  |                  |    |        | |||          |  |    | |   |  |          
search RasMol script viewer Motif-ligand binding stats  MYRISTYL ..                        ^*****|       |  |        | | |   | || | |       | |    |  | |  |                 | |||            ^*****                 .. ^*****                  ^*****        | |||          |  |    | |   |  |          
search RasMol script viewer Motif-ligand binding stats  IG_MHC ..                           |  |       |  |        | | |   | || | |       | |    |  | |  |                 | |||                                   .. | |                                   | |||          |  |    **^****  |          
search RasMol script viewer Motif-ligand binding stats  asxturn ..                           |  |       |  |        | | |   ***| | |       | |    |  | |  |                 | |||                                   .. | |                                   | |||          |  |          |  |          
search RasMol script viewer Motif-ligand binding stats  betaturn ..                           |  |       |  |        | | |      | | |       | |    |  | |  |                 ****|                                   .. | |                                   ****|          |  |          ****          
search RasMol script viewer Motif-ligand binding stats  nest ..                           |  |       |  |        | ***      *****       ***    |  | |  |                   ***                                   .. | |                                     ***          |  |                        
search RasMol script viewer Motif-ligand binding stats  niche ..                           ****       ****        | |                           **** ****                                                         .. ***                                                  ****                        
search RasMol script viewer Motif-ligand binding stats  stturn ..                                                  ***                                                                                             ..                                                                                  

Assembly 2     View the assembly/model: ( JMolViewer Download PDB file RasMol script viewer AstexViewer™@MSD-EBI )
Motif search   chain:    Sequence numbers: 
   Using:   φ/ψ    residues code    secondary structures   
 coordinates of:  Cαs Side-chain
 
      View the fragment: rasmol script JMol viewer
chain B : T-CELL SURFACE GLYCOPROTEIN CD4
member of: GENE3D:searchG3DSA_2.60.40.10PANTHER:searchPTHR11422/searchPTHR11422_SF0PFAM:searchPF05790/searchPF07686/searchPF09191PROSITE PROFILES:searchPS50835, SMART:searchSM00406/searchSM00409SUPERFAMILY:searchSSF48726UniProt:searchP01730
JMol viewer RasMol script viewer  NAG 512O  ..                                                                                                                                                                               
sec str:  ...eeeeee....eee...........eeee.....eeeeee..eeee..hhhhh.ee.hhhhhhhh...eee........eeeeeee...eeeeeeeeeeee............eeeeee.......eeeee.....eeee..eeee...hhhhheeeeeeeee..eeeeeeeee.
sequence :  ..KKVVLGKKGDTVELTCTASQKKSIQFHWKNSNQIKILGNQGSFLTKGPSKLNDRADSRRSLWDQGNFPLIIKNLKIEDSDTYICEVEDQKEEVQLLVFGLTANSDTHLLQGQSLTLTLESPPGSSPSVQCRSPRGKNIQGGKTLSVSQLELQDSGTWTCTVLQNQKKVEFKIDIV
seq num:  ..1         11        21        31        41        51        61        71        81        91        101       111       121       131       141       151       161       171  
search RasMol script viewer Motif-ligand binding stats  PKC_PHOSPHO_SITE ..    |  |          ^**          | | |||  | |     | ||  | ^**||||| |    |  |||  |  |                |    |  | | ||   |    | ||   |   ^** |          |  ||  ||    |  |  |         
search RasMol script viewer Motif-ligand binding stats  CK2_PHOSPHO_SITE ..    |  |                       | | |||  | |     | ||  |   |^***| |    |  |||  |  |                |    |  | | ||   |    | ||   |     | |          ^***|  ||    |  |  |         
search RasMol script viewer Motif-ligand binding stats  TYR_PHOSPHO_SITE ..    |  |                       | | |||  | |     | ||  |   | || | |    |  |*******^                |    |  | | ||   |    | ||   |     | |              |  ||    |  |  |         
search RasMol script viewer Motif-ligand binding stats  MYRISTYL ..    |  |                       | | ||^*****     | ||  |   | || | |    |  | |  |                   ^*****  | | ^*****    | ^*****     | |              |  |^*****  |  |         
search RasMol script viewer Motif-ligand binding stats  AMIDATION ..    ^***                       | | ||   | |     | ||  |   | || | |    |  | |  |                        |  | |  |        |  |         | |              |  |        |  |         
search RasMol script viewer Motif-ligand binding stats  betabulge ..                               | | **   | |     | ||  |   | || | |    |  | |  |                        |  | |  |        |  |         | |              |  |        |  |         
search RasMol script viewer Motif-ligand binding stats  betaturn ..                               | |      | |     | ||  |   ****** |    |  | |  |                        |  | |  |        ****         | |              ****        ****         
search RasMol script viewer Motif-ligand binding stats  nest ..                               ***      | |     | ||  |        ***    |  | |  |                        |  | |  |        |  |         ***              |  |                     
search RasMol script viewer Motif-ligand binding stats  niche ..                                        ***     | |****               **** ****                        **** ****        ****                          ****                     
search RasMol script viewer Motif-ligand binding stats  stturn ..                                                ***                                                                                                                            

chain C : PGT124 LIGHT CHAIN
JMol viewer RasMol script viewer  MAN 510O  ..                                             *               *                                                                                                                                                    
JMol viewer RasMol script viewer  MAN 509O  ..                                           ***             **|                                                                                                                                                    
JMol viewer RasMol script viewer  MAN 508O  ..                       *                   |||             |**                                                                                                                                                    
sec str:  ....eeeeee....eeee.........eeeeeee......eeee.............ee...........eeee...hhhhheeeeeeee............eeeeeee.........eee..hhhhhhh..eeeeeeeeee.....eeeeee..ee....eee..........eeeeeeeeehhhhhhhh..eeeeeee..eeeeeee...
sequence :  ..YVSPLSVALGETARISCGRQALGSRAVQWYQHKPGQAPILLIYNNQDRPSGIPERFSGTPDINFGTTATLTISGVEVGDEADYYCHMWDSRSGFSWSFGGATRLTVLSQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHKSYSCQVTHEGSTVEKTVAPT
seq num:  ..5         17        27        37        47        57        66        74        84        94        101       111       121       131       141       151       161       171       181       191       201       
search RasMol script viewer Motif-ligand binding stats  PKC_PHOSPHO_SITE ..           ^**  | |                     ||| | |     |  |    | | ||   |  || || ||        | |     | |                      |  |  | |                            |    |     | |             | ^** | |   |  |  |      
search RasMol script viewer Motif-ligand binding stats  CK2_PHOSPHO_SITE ..                | |                     ||| | |     |  |    | | ||   |  ^***| ||        | |     | |                      ^***  | |                            |    |     | |             |  |  | |   |  ^***      
search RasMol script viewer Motif-ligand binding stats  MYRISTYL ..                | |                     ||| | |     |  |    | | ^*****   ^*****|        | |     | |                            | |                            ^*****     | |             |  |  | |   |            
search RasMol script viewer Motif-ligand binding stats  IG_MHC ..                | |                     ||| | |     |  |    | |  |          |  |        | |     | |                            | |                                       | |             |  |  **^****            
search RasMol script viewer Motif-ligand binding stats  asxturn ..                | |                     ||| | |     |  |    | |  |          |  |        ***     | |                            | |                                       | |             |  |                     
search RasMol script viewer Motif-ligand binding stats  betabulge ..                | |                     **| | |     |  |    | |  |          |  |                | |                            | |                                       | |             |  |                     
search RasMol script viewer Motif-ligand binding stats  nest ..                ***                       | | |     |  |    | |  |          |  |                | |                            ***                                       ***             |  |                     
search RasMol script viewer Motif-ligand binding stats  niche ..                                          *****     ****    ******          ****                | |                                                                                      ****                     
search RasMol script viewer Motif-ligand binding stats  stturn ..                                                                                                ***                                                                                                               

chain D : PGT124 HEAVY CHAIN
JMol viewer RasMol script viewer  MAN 509O  ..                                                                                                     *                                           ..                                                                                
JMol viewer RasMol script viewer  MAN 508O  ..                                                                                                     *                                           ..                                                                                
JMol viewer RasMol script viewer  BMA 503O  ..                                                                                                     |*                                          ..                                                                                
JMol viewer RasMol script viewer  NAG 502O  ..                                                                                                     |* ***                                      ..                                                                                
JMol viewer RasMol script viewer  NAG 501O  ..                                                                                                     || |||                                      ..                                                                                
JMol viewer RasMol script viewer  MAN 504O  ..                                                                                                     || |||                                      ..                                                                                
JMol viewer RasMol script viewer  MAN 506O  ..                                                                                                    *|| |||                                      ..                                                                                
sec str:  ....eeee...ee.....eeeeeee........eeeeeee.....eeeeeee.....eee.hhhh..eeeeee....eeeeee...hhhhheeeeeeeeeeeee..........eeeeeeeee...eeeee.........eeee......eeeeeeeeeee.....eeee........eee..........eeeeeeeeee.........eeeee.........ee...
sequence :  ..VQLQESGPGLVRPSETLSVTCIVSGGSISNYYWTWIRQSPGKGLEWIGYISDRETTTYNPSLNSRAVISRDTSKNQLSLQLRSVTTADTAIYFCATARRGQRIYGVVSFGEFFYYYYMDVWGKGTAVTVSSASTKGPSVFPLAPS..GTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP
seq num:  ..2         12        22        32        42        52        62        72        82        89        99        100       103       113       141  ..152       162       172       182       192       202       212       222       
search RasMol script viewer Motif-ligand binding stats  PKC_PHOSPHO_SITE ..       | | |  |         | |||||       |  |      | ^**||   |  | | |     ^** |        || ||      ^**        || ||            |    |   ^**         ^..    |               | ||    |        | |||            | |   | |   | || |  |     
search RasMol script viewer Motif-ligand binding stats  CK2_PHOSPHO_SITE ..       | | |  |         | |||||       |  |      | ^***|   |  | | |       | |        ^***|                 |^***            |    |                ..    |               | ||    |        | |||            | |   | |   | || ^***     
search RasMol script viewer Motif-ligand binding stats  TYR_PHOSPHO_SITE ..       | | |  |         | |||||       |  *******^   | |   |  | | |       | |        || ||                 |  |             |    |                ..    |               | ||    |        | |||            | |   | |   | || |        
search RasMol script viewer Motif-ligand binding stats  MYRISTYL ..       | | |  |         ^*****|       |  |          | |   |  | | |       | |        || ||                 |  |             ^*****                ..*****               | |^*****        | |||            | |   | |   | || |        
search RasMol script viewer Motif-ligand binding stats  IG_MHC ..       | | |  |           ||| |       |  |          | |   |  | | |       | |        || ||                 |  |                                   ..                    | |              | |||            | |   **^**** || |        
search RasMol script viewer Motif-ligand binding stats  betaturn ..       | | |  |           ||| |       ****          | |   **** | |       | |        ****|                 |  |                                   ..                    | |              ****|            | |         **** |        
search RasMol script viewer Motif-ligand binding stats  gammaturn ..       *** |  |           ||| |       |  |          | |      | | |       | |         |  |                 |  |                                   ..                    | |                | |            | |           |  |        
search RasMol script viewer Motif-ligand binding stats  nest ..           |  |           ||| |       |  |          ***      *****       ***         |  |                 |  |                                   ..                    | |                ***            | |           |  |        
search RasMol script viewer Motif-ligand binding stats  niche ..           ****           |****       ****                                           ****                 ****                                   ..                    ***                               | |           ****        
search RasMol script viewer Motif-ligand binding stats  stturn ..                          ***                                                                                                                    ..                                                      ***                       

chain O : SURFACE PROTEIN GP160
member of: GENE3D:searchG3DSA_2.170.40.20PFAM:searchPF00516SUPERFAMILY:searchSSF56502UniProt:searchP20871
JMol viewer RasMol script viewer  CL 518O  ..                                                                                                                                          ..     *                                                                                                             *                                                 
JMol viewer RasMol script viewer  NAG 517O  ..                                                                                                 *                                        ..     |                                                                                                             |     *                                           
JMol viewer RasMol script viewer  NAG 516O  ..                                                                                                 |                                        ..     |                                                            *  *                                             |     |                                           
JMol viewer RasMol script viewer  NAG 515O  ..                                                                                                 |                                        ..     |                                           *             * *|  |                                             |     |                                           
JMol viewer RasMol script viewer  NAG 514O  ..                                                                                                 |                                        ..     |       *   *                               |             | ||  |        *  **  *                             |     |                                           
JMol viewer RasMol script viewer  NAG 513O  ..                                                                                                 |                              * *       ..     |     **|   |                               |             | ||  |        |  ||  |                             |     |                                           
JMol viewer RasMol script viewer  NAG 512O  ..                                                                                                 |             * **             | |       ..     |     |||   |                               |             | ||  |        |  ||  |                             |     |                                           
JMol viewer RasMol script viewer  NAG 511O  ..                                                                                         *       *             | ||             | |       ..     |     |||   |                               |             | ||  |        |  ||  |                             |  ***|                                           
JMol viewer RasMol script viewer  NAG 502O  ..                                                                                         |       |             | ||             | |       ..     |     |||   |                               |             | ||  |        |  ||  |                             |  ||||                                           
JMol viewer RasMol script viewer  NAG 501O  ..                                                                                         |       |             | ||             | *       ..     |  * *|||   |                               |             | ||  |        |  ||  |  *                          |  ||||                                           
sec str:  .........hhhhhhhhhhhhhhhhhh...eeee..eeee....................eeeeee.............eeee.............eee.........eee..........eeeeeeeeeeeeeee..............eeeeehhhhhhhhhhhhhhhhhhh...eeee......hhhhhheeeee..eeeee.......eee.....ee......eeeeeeeee.eee......eee........eeeeeeeeeeeeee........eeeeee...hhhhhhhhhhh.eeeee.
sequence :  ..DFNMWKNNMVEQMQEDVINLWDQSLKPCVKLTGGSVITQACPKVSFEPIPIHYCAPAGFAILKCNNKTFNGKGQCKNVSTVQCTHGIRPVVSTQLLLNGSLAEEKVVIRSDNFTDNAKTIIVQLNESVKINCTRPSNN..IIGDIRQAHCNISRAQWNNTLKQIVEKLREQFNNKTIVFTHSSGGDPEIVMHSFNCGGEFFYCNSTQLFNSTWNDTEKSSGTEGNDTIILPCRIKQIINMWQEVGKAMYAPPIKGQIRCSSNITGLLLTRDGGKNESEIEIFRPGGGDMRDNWRSELYKYKVVKI
seq num:  ..92        102       112       122       205       215       225       235       245       255       265       275       285       295     ..322       332       342       352       363       373       383       393       403       417       427       437       447       457       467       477       487  
search RasMol script viewer Motif-ligand binding stats  ASN_GLYCOSYLATION ..  ||| | |              | |       |    |                |  |    | ^***| ||   ^***            | || ^*** |        ^*** ||      ^***| ^*** |^*..          ^*** | ^***|           ^***    ||| | |||  |          ^***  ^***^***| || | ^***      | |  |  |           |    | ^***    |    ^***||       | |      |  |     
search RasMol script viewer Motif-ligand binding stats  PKC_PHOSPHO_SITE ..  ||| | |              ^**       |    |                |  |    | |   | ||    |              | ||  ||  |        | || ||        ^**    | |  ..               |   ^**                   ||| | |||  |                  |  |^** || |  |        | |  |  |           |    |    |    |    ||||||       | |      |  |     
search RasMol script viewer Motif-ligand binding stats  CK2_PHOSPHO_SITE ..  ||| | |                        |    |                |  |    | |   | ||    |              | ||  |^***        | || ||               | |  ..               |   |                     |^*** |||  |                  ^***    ^***  |        | |  |  |           |    |    |    |    ||^***       | |      |  |     
search RasMol script viewer Motif-ligand binding stats  MYRISTYL ..  ||| | |                        ^*****                |  |    | |   | |^*****              | ||  |            | || ||               | |  ..               |   |                     | | | |||  |                           ^*****        | |  |  |           ^*****    ^*****    |||||        | |      |  |     
search RasMol script viewer Motif-ligand binding stats  alphabetamotif ..  ||| | |                                              |  |    | |   | |                    | ||  |            | || ||               | |  ..               |   |                     | | *****  |                           | |           | |  |  |                               |||||        | |      |  |     
search RasMol script viewer Motif-ligand binding stats  asxturn ..  *** ***                                              |  |    | |   | |                    | ||  |            ******|               | |  ..               |   |                     | | | ||   |                           | |           | |  |  |                               |||||        ***      |  |     
search RasMol script viewer Motif-ligand binding stats  betaturn ..   |  |                                                |  |    | |   | |                    | ||  |            |  |  |               | |  ..               |   |                     | | ****   |                           | |           | |  |  |                               |||||                 |  |     
search RasMol script viewer Motif-ligand binding stats  gammaturn ..   |  |                                                |  |    | |   | |                    ***|  |            |  |  |               | |  ..               |   |                     | |   |    |                           | |           | |  |  |                               |||||                 |  |     
search RasMol script viewer Motif-ligand binding stats  nest ..   |  |                                                |  |    | |   ***                       |  |            |  |  |               | |  ..               |   |                     | |   |    |                           ***           | |  |  |                               *****                 |  |     
search RasMol script viewer Motif-ligand binding stats  niche ..   ****                                                ****    ***                             ****            *******               ***  ..               |   |                     | |   |    |                                         ***  ****                                                     ****     
search RasMol script viewer Motif-ligand binding stats  ststaple ..                                                                                                                                          ..               *****                     | |   ******                                                                                                                
search RasMol script viewer Motif-ligand binding stats  stturn ..                                                                                                                                          ..                                         ***                                                                                                                         

Assembly 3     View the assembly/model: ( JMolViewer Download PDB file RasMol script viewer AstexViewer™@MSD-EBI )
Motif search   chain:    Sequence numbers: 
   Using:   φ/ψ    residues code    secondary structures   
 coordinates of:  Cαs Side-chain
 
      View the fragment: rasmol script JMol viewer
chain H : T-CELL SURFACE GLYCOPROTEIN CD4
member of: GENE3D:searchG3DSA_2.60.40.10PANTHER:searchPTHR11422/searchPTHR11422_SF0PFAM:searchPF05790/searchPF07686/searchPF09191PROSITE PROFILES:searchPS50835, SMART:searchSM00406/searchSM00409SUPERFAMILY:searchSSF48726UniProt:searchP01730
JMol viewer RasMol script viewer  NAG 511K  ..                            *                                                                                                                                                   
sec str:  ....eeeee....eee............eee.....eeeeee..eeee........ee.hhhhhh.....eee...hhhhheeeeee....eeeeeeeeeeeee.............eeee.......eeeee.....eeee...............eeeeeeee..eeeeeeee...
sequence :  ..KKVVLGKKGDTVELTCTASQKKSIQFHWKNSNQIKILGNQGSFLTKGPSKLNDRADSRRSLWDQGNFPLIIKNLKIEDSDTYICEVEDQKEEVQLLVFGLTANSDTHLLQGQSLTLTLESPPGSSPSVQCRSPRGKNIQGGKTLSVSQLELQDSGTWTCTVLQNQKKVEFKIDIVV
seq num:  ..1         11        21        31        41        51        61        71        81        91        101       111       121       131       141       151       161       171   
search RasMol script viewer Motif-ligand binding stats  PKC_PHOSPHO_SITE ..    |  |          ^**          | |   |  | |   | | ||  | ^**||||           ||  |  |                |    |      |    |    | ||   |   ^**            | |||| ||    |                
search RasMol script viewer Motif-ligand binding stats  CK2_PHOSPHO_SITE ..    |  |                       | |   |  | |   | | ||  |  ||^***           ||  |  |                |    |      |    |    | ||   |                  ^***|| ||    |                
search RasMol script viewer Motif-ligand binding stats  TYR_PHOSPHO_SITE ..    |  |                       | |   |  | |   | | ||  |  || ||            *******^                |    |      |    |    | ||   |                    |||| ||    |                
search RasMol script viewer Motif-ligand binding stats  MYRISTYL ..    |  |                       | |   ^*****   | | ||  |  || ||             |  |                   ^*****      ^*****    | ^*****                    |||| |^*****                
search RasMol script viewer Motif-ligand binding stats  AMIDATION ..    ^***                       | |      | |   | | ||  |  || ||             |  |                                         |  |                        |||| |                      
search RasMol script viewer Motif-ligand binding stats  betaturn ..                               | |      | |   | | ||  |  *****             ****                                         |  |                        ||****                      
search RasMol script viewer Motif-ligand binding stats  gammaturn ..                               | |      | |   *** ||  |                    |  |                                         |  |                        |*** |                      
search RasMol script viewer Motif-ligand binding stats  nest ..                               ***      | |     | ||  |                    |  |                                         |  |                        ***  |                      
search RasMol script viewer Motif-ligand binding stats  niche ..                                        ***     | |****                    ****                                         ****                          ****                      
search RasMol script viewer Motif-ligand binding stats  stturn ..                                                ***                                                                                                                             

chain I : PGT124 LIGHT CHAIN
JMol viewer RasMol script viewer  MAN 510K  ..                                             *               *                                                                                                                                                    
JMol viewer RasMol script viewer  MAN 509K  ..                                           ***             **|                                                                                                                                                    
JMol viewer RasMol script viewer  MAN 508K  ..                                           |||             |**                                                                                                                                                    
JMol viewer RasMol script viewer  MAN 505K  ..                                           |||             |||                                                                                                                                                    
sec str:  ....eeeeee....eeee........eeeeeeee......eeee.............ee...........eeee...hhhhheeeeeeeee...........eeeeeee.......eeeee..hhhhhhh..eeeeeeeeee.....eeeeee..ee....eee..........eeeeeeeeehhhhhhh...eeeeee....eeeeee...
sequence :  ..YVSPLSVALGETARISCGRQALGSRAVQWYQHKPGQAPILLIYNNQDRPSGIPERFSGTPDINFGTTATLTISGVEVGDEADYYCHMWDSRSGFSWSFGGATRLTVLSQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHKSYSCQVTHEGSTVEKTVAPT
seq num:  ..5         17        27        37        47        57        66        74        84        94        101       111       121       131       141       151       161       171       181       191       201       
search RasMol script viewer Motif-ligand binding stats  PKC_PHOSPHO_SITE ..           ^**                          || | |  |  ||  |      | ||   |  || || ||                | |                      |  |  | |           | |       | |    |    |   | |||             | ^** | |   |  |  |      
search RasMol script viewer Motif-ligand binding stats  CK2_PHOSPHO_SITE ..                                        || | |  |  ||  |      | ||   |  ^***| ||                | |                      ^***  | |           | |       | |    |    |   | |||             |  |  | |   |  ^***      
search RasMol script viewer Motif-ligand binding stats  MYRISTYL ..                                        || | |  |  ||  |      | ^*****   ^*****|                | |                         |  | |           | |       | |    ^*****   | |||             |  |  | |   |            
search RasMol script viewer Motif-ligand binding stats  IG_MHC ..                                        || | |  |  ||  |      |  |         || ||                | |                         |  | |           | |       | |             | |||             |  |  **^****            
search RasMol script viewer Motif-ligand binding stats  asxturn ..                                        || | |  |  ||  |      |  |         || ||                | |                         |  | |           | |       | |             | ***             |  |                     
search RasMol script viewer Motif-ligand binding stats  betabulge ..                                        ** | |  |  ||  |      |  |         || ||                | |                         |  | |           | |       | |             | |||             |  |                     
search RasMol script viewer Motif-ligand binding stats  betaturn ..                                           | |  ****|  |      |  |         ****|                | |                         **** |           | |       | |             ****|             |  |                     
search RasMol script viewer Motif-ligand binding stats  gammaturn ..                                           ***  |  ||  |      |  |          |  |                | |                            | |           ***       | |               | |             |  |                     
search RasMol script viewer Motif-ligand binding stats  nest ..                                                |  ||  |      |  |          |  |                | |                            ***                     | |               ***             |  |                     
search RasMol script viewer Motif-ligand binding stats  niche ..                                                ********      ****          ****                | |                                                    ***                               ****                     
search RasMol script viewer Motif-ligand binding stats  stturn ..                                                                                                ***                                                                                                               

chain J : PGT124 HEAVY CHAIN
JMol viewer RasMol script viewer  MAN 509K  ..                                                                                                     *                                           ..                                                                                 
JMol viewer RasMol script viewer  MAN 508K  ..                                                                                                     *                                           ..                                                                                 
JMol viewer RasMol script viewer  BMA 503K  ..                                                                                                     |*                                          ..                                                                                 
JMol viewer RasMol script viewer  NAG 502K  ..                                                                                                     |* ***                                      ..                                                                                 
JMol viewer RasMol script viewer  NAG 501K  ..                                                                                                     || |||                                      ..                                                                                 
JMol viewer RasMol script viewer  MAN 506K  ..                                                                                                    *|| |||                                      ..                                                                                 
sec str:  ....eeee...ee.....eeeeeee...hhhhh.eeeeee.....eeeeeee.....eee.hhhh..eeeeee....eeeeee........eeeeeee.eeeeee..hhhhh.eeeeee.......eeeee........eeeee.......eeeeeeeee.......eeee.........ee.............eeeeeee.hhh....eeeeeee....eeeeeee..
sequence :  ..VQLQESGPGLVRPSETLSVTCIVSGGSISNYYWTWIRQSPGKGLEWIGYISDRETTTYNPSLNSRAVISRDTSKNQLSLQLRSVTTADTAIYFCATARRGQRIYGVVSFGEFFYYYYMDVWGKGTAVTVSSASTKGPSVFPLAPS..GGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP
seq num:  ..2         12        22        32        42        52        62        72        82        89        99        100       103       113       141  ..151       161       171       181       191       201       211       221        
search RasMol script viewer Motif-ligand binding stats  PKC_PHOSPHO_SITE ..                        | |||||       |  |      | ^**||   | || | |    |^** |        |||||      ^**       |||||||     | |   |    |   ^**         ^..|    |               | ||| ||||       | |||         || ||    | |   || |||  |     
search RasMol script viewer Motif-ligand binding stats  CK2_PHOSPHO_SITE ..                        | |||||       |  |      | ^***|   | || | |    |  | |        ^***|                ||^***|     | |   |    |                ..|    |               | ||| ||||       | |||         || ||    | |   || ||^***     
search RasMol script viewer Motif-ligand binding stats  TYR_PHOSPHO_SITE ..                        | |||||       |  *******^ | |||   | || | |    |  | |        ||| |                || ||||     | |   |    |                ..|    |               | ||| ||||       | |||         || ||    | |   || ||         
search RasMol script viewer Motif-ligand binding stats  MYRISTYL ..                        ^*****|       |  |        | |||   | || | |    |  | |        ||| |                || ||||     | |   ^*****                ..^*****               | |^*****|       | |||         || ||    | |   || ||         
search RasMol script viewer Motif-ligand binding stats  IG_MHC ..                          ||| |       |  |        | |||   | || | |    |  | |        ||| |                || ||||     | |                         ..                     | | | || |       | |||         || ||    **^****| ||         
search RasMol script viewer Motif-ligand binding stats  asxturn ..                          ||| |       |  |        | |||   ***| | |    |  | |        ||| |                || ||||     | |                         ..                     | | | || |       | |||         || ||          || ||         
search RasMol script viewer Motif-ligand binding stats  betabulgeloop ..                          ||| |       |  |        | |||      | | |    ******        ||| |                || ||||     | |                         ..                     | | | || |       | |||         || ||          || ||         
search RasMol script viewer Motif-ligand binding stats  betaturn ..                          ||| |       |  |        ****|      | | |       | |        ||| |                *****||     | |                         ..                     | | | || |       ****|         ****|          ****|         
search RasMol script viewer Motif-ligand binding stats  gammaturn ..                          ||| |       |  |          | |      | | |       | |        ||| |                   |***     | |                         ..                     | | ***| |         | |          |  |           |  |         
search RasMol script viewer Motif-ligand binding stats  nest ..                          ||| |       |  |          ***      *****       ***        ||| |                   ***      | |                         ..                     | |    | |         ***          |  |           |  |         
search RasMol script viewer Motif-ligand binding stats  niche ..                          |****       ****                     ***                  |****                            ***                         ..                     ***    ***                      ****           ****         
search RasMol script viewer Motif-ligand binding stats  stturn ..                          ***                                                       ***                                                          ..                                                                                 

chain K : SURFACE PROTEIN GP160
member of: GENE3D:searchG3DSA_2.170.40.20PFAM:searchPF00516SUPERFAMILY:searchSSF56502UniProt:searchP20871
JMol viewer RasMol script viewer  CL 516K  ..                                                                                                                                      *   ..     *                                                                                                             * *                                               
JMol viewer RasMol script viewer  NAG 515K  ..                                                                                                                                      |   ..     |                                            *            * *                          *                      | |                                               
JMol viewer RasMol script viewer  NAG 514K  ..                                                                                                                                      |   ..     |       **  *                                |            | |            *  *          |                      | |                                               
JMol viewer RasMol script viewer  NAG 513K  ..                                                                                                                                * *   |   ..     |     **||  |                                |            | |            |  |          |                      | |                                               
JMol viewer RasMol script viewer  NAG 512K  ..                                                                                         *      **                              | |   |   ..     |     ||||  |                                |            | |            |  |          |                      | | **                                            
JMol viewer RasMol script viewer  NAG 511K  ..                                                                                         |      ||             * **             | |   |   ..     |     ||||  |                                |            | |            |  |          |                      | | ||                                            
JMol viewer RasMol script viewer  NAG 502K  ..                                                                                         |      ||             | ||             | |   |   ..     *     ||||  |                                |            | |            |  |          |                      | | ||                                            
JMol viewer RasMol script viewer  NAG 501K  ..                                                                                         |      ||             | ||             | *   |   ..     |  * *||||  |                                |            | |            |  |      *   |                      | | ||                                            
sec str:  ..........hhhhhhhhhhhhhhhhh...eee.....ee....................eee.................................eee.........eee..........eeeeeeeeeeeeee...............eeeeehhhhhhhhhhhhhhhhhhh....eee......hhhhhheeeee..eeeee.......eee.....ee......eeeeeeeee.eee......eee.........eeeeeeeeeeeee.........eeeee...hhhhhhhhhhh...eee.
sequence :  ..DFNMWKNNMVEQMQEDVINLWDQSLKPCVKLTGGSVITQACPKVSFEPIPIHYCAPAGFAILKCNNKTFNGKGQCKNVSTVQCTHGIRPVVSTQLLLNGSLAEEKVVIRSDNFTDNAKTIIVQLNESVKINCTRPSNN..IIGDIRQAHCNISRAQWNNTLKQIVEKLREQFNNKTIVFTHSSGGDPEIVMHSFNCGGEFFYCNSTQLFNSTWNDTEKSSGTEGNDTIILPCRIKQIINMWQEVGKAMYAPPIKGQIRCSSNITGLLLTRDGGKNESEIEIFRPGGGDMRDNWRSELYKYKVVKI
seq num:  ..92        102       112       122       205       215       225       235       245       255       265       275       285       295     ..322       332       342       352       363       373       383       393       403       417       427       437       447       457       467       477       487  
search RasMol script viewer Motif-ligand binding stats  ASN_GLYCOSYLATION ..  ||| | |       |  ||  | |       || | |                |  |    | ^***| ||   ^***            | || ^*** |        ^***  |      ^***| ^*** |^*.. | |      ^***   ^***|           ^***     |  | |||  |          ^***  ^***^***| || | ^***           |  |           |    | ^***    || | ^***||         |  || ||        
search RasMol script viewer Motif-ligand binding stats  PKC_PHOSPHO_SITE ..  ||| | |       |  ||  ^**       || | |                |  |    | | | | ||    |              | ||  ||  |        |  |  |        ^**    | |  .. | |               ^**                    |  | |||  |                  |  |^** || |  |             |  |           |    |    |    || |  || ||         |  || ||        
search RasMol script viewer Motif-ligand binding stats  CK2_PHOSPHO_SITE ..  ||| | |       |  ||  |         || | |                |  |    | | | | ||    |              | ||  |^***        |  |  |               | |  .. | |                                      ^*** |||  |                  ^***    ^***  |             |  |           |    |    |    || |  |^***         |  || ||        
search RasMol script viewer Motif-ligand binding stats  MYRISTYL ..  ||| | |       |  ||  |         ^*****                |  |    | | | | |^*****              | ||  |            |  |  |               | |  .. | |                                         | |||  |                           ^*****             |  |           ^*****    ^*****| |  || |          |  || ||        
search RasMol script viewer Motif-ligand binding stats  alphabetamotif ..  ||| | |       *****  |          | |                  |  |    | | | | |                    | ||  |            |  |  |               | |  .. | |                                         *****  |                           | |                |  |                           | |  || |          ********        
search RasMol script viewer Motif-ligand binding stats  asxturn ..  *** ***       |  |   |          | |                  |  |    | | | ***                    | ||  |            |  |  |               | |  .. | |                                         | ||   |                           | |                |  |                           | |  || |          |  |  |         
search RasMol script viewer Motif-ligand binding stats  betaturn ..   |  |         ****   |          | |                  ****    | | | | |                    | ||  |            |  |  |               | |  .. | |                                         ****   |                           | |                |  |                           | |  || |          *******         
search RasMol script viewer Motif-ligand binding stats  gammaturn ..   |  |            |   |          | |                  |  |    | | | | |                    ***|  |            |  |  |               | |  .. | |                                           |    |                           | |                |  |                           | |  || |                          
search RasMol script viewer Motif-ligand binding stats  nest ..   |  |            |   |          ***                  |  |    | | | ***                       |  |            |  |  |               | |  .. | |                                           |    |                           ***                |  |                           ***  || |                          
search RasMol script viewer Motif-ligand binding stats  niche ..   ****            |   |                               ****    *****                           ****            *******               ***  .. ***                                           |    |                                              ****                             *******                          
search RasMol script viewer Motif-ligand binding stats  ststaple ..                   *****                                                                                                                  ..                                               ******                                                                                                                

Assembly 4     View the assembly/model: ( JMolViewer Download PDB file RasMol script viewer AstexViewer™@MSD-EBI )
Motif search   chain:    Sequence numbers: 
   Using:   φ/ψ    residues code    secondary structures   
 coordinates of:  Cαs Side-chain
 
      View the fragment: rasmol script JMol viewer
chain L : T-CELL SURFACE GLYCOPROTEIN CD4
member of: GENE3D:searchG3DSA_2.60.40.10PANTHER:searchPTHR11422/searchPTHR11422_SF0PFAM:searchPF05790/searchPF07686/searchPF09191PROSITE PROFILES:searchPS50835, SMART:searchSM00406/searchSM00409SUPERFAMILY:searchSSF48726UniProt:searchP01730
JMol viewer RasMol script viewer  NAG 516A  ..                                                                                                                                                                             
sec str:  ...eeee....eee...........eeee.....eeeeee..eeee........ee.hhhhhhhh...eee...hhhhheeeeeee...eeeeeeeee...............eeee.........eeeee.....eeeee.eeee...hhhhheeeeeeeee..eeeeeeeee.
sequence :  ..VVLGKKGDTVELTCTASQKKSIQFHWKNSNQIKILGNQGSFLTKGPSKLNDRADSRRSLWDQGNFPLIIKNLKIEDSDTYICEVEDQKEEVQLLVFGLTANSDTHLLQGQSLTLTLESPPGSSPSVQCRSPRGKNIQGGKTLSVSQLELQDSGTWTCTVLQNQKKVEFKIDIV
seq num:  ..3         13        23        33        43        53        63        73        83        93        103       113       123       133       143       153       163          
search RasMol script viewer Motif-ligand binding stats  PKC_PHOSPHO_SITE ..  |  |         |^**        | | | |||  | |     | || || ^**| ||| |        || ||  |                |    || |   |    |    | ||   |   ^**      | |   |  ||  ||    |               
search RasMol script viewer Motif-ligand binding stats  CK2_PHOSPHO_SITE ..  |  |         | |         | | | |||  | |     | || ||   |^***| |        || ||  |                |    || |   |    |    | ||   |            | |   ^***|  ||    |               
search RasMol script viewer Motif-ligand binding stats  TYR_PHOSPHO_SITE ..  |  |         | |         | | | |||  | |     | || ||   |  | | |        *******^                |    || |   |    |    | ||   |            | |       |  ||    |               
search RasMol script viewer Motif-ligand binding stats  MYRISTYL ..  |  |         | |         | | | ||^*****     | || ||   |  | | |        || ||                   ^*****| |   ^*****    | ^*****            | |       |  |^*****               
search RasMol script viewer Motif-ligand binding stats  AMIDATION ..  ^***         | |         | | | ||   | |     | || ||   |  | | |        || ||                         | |             |  |                | |       |  |                     
search RasMol script viewer Motif-ligand binding stats  alphabetamotif ..               | |         | | | ||   | |     | *****   |  | | |        || ||                         | |             |  |                | |       |  |                     
search RasMol script viewer Motif-ligand binding stats  asxturn ..               | |         *** | ||   | |     | || ||   |  | | |        || ||                         | |             |  |                | |       |  |                     
search RasMol script viewer Motif-ligand binding stats  betabulge ..               | |           | | **   | |     | || ||   |  | | |        || ||                         | |             |  |                | |       |  |                     
search RasMol script viewer Motif-ligand binding stats  betaturn ..               | |           | |      | |     | ****|   **** | |        ****|                         | |             |  |                | |       |  |                     
search RasMol script viewer Motif-ligand binding stats  gammaturn ..               | |           | |      | |     | ||  |        | |         |  |                         | |             |  |                ***       |  |                     
search RasMol script viewer Motif-ligand binding stats  nest ..               | |           ***      | |     | ||  |        ***         |  |                         | |             |  |                          |  |                     
search RasMol script viewer Motif-ligand binding stats  niche ..               ***                    ***     | |****                    ****                         ***             ****                          ****                     
search RasMol script viewer Motif-ligand binding stats  stturn ..                                              ***                                                                                                                            

chain M : PGT124 LIGHT CHAIN
JMol viewer RasMol script viewer  MAN 510A  ..                                             *             * *                                                                                                                                                    
JMol viewer RasMol script viewer  MAN 509A  ..                                           ***             **|                                                                                                                                                    
JMol viewer RasMol script viewer  MAN 508A  ..                       *                   |||             |**                                                                                                                                                    
JMol viewer RasMol script viewer  MAN 505A  ..                       |                   |||             |||                                                                                                                                                    
sec str:  ...eeeeeee....eeee........eeeeeeee......eeee.............ee...........eeee...hhhhh.eeeeeeee...........eeeeeee.......eeeee..hhhhhh...eeeeeeeeee.....eeeeee..ee....eee...ee.....eeeeeeeeehhhhhhh...eeeeeee..eeeeeee...
sequence :  ..YVSPLSVALGETARISCGRQALGSRAVQWYQHKPGQAPILLIYNNQDRPSGIPERFSGTPDINFGTTATLTISGVEVGDEADYYCHMWDSRSGFSWSFGGATRLTVLSQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHKSYSCQVTHEGSTVEKTVAPT
seq num:  ..5         17        27        37        47        57        66        74        84        94        101       111       121       131       141       151       161       171       181       191       201       
search RasMol script viewer Motif-ligand binding stats  PKC_PHOSPHO_SITE ..           ^**  | |             |  |    ||| | | |  ||  |      | ||   |  || || ||              | | |                      |  |  | |      |  | | |       | |  | ||   |   | |||         | | | ^** | |   |  |  |      
search RasMol script viewer Motif-ligand binding stats  CK2_PHOSPHO_SITE ..                | |             |  |    ||| | | |  ||  |      | ||   |  ^***| ||              | | |                      ^***  | |      |  | | |       | |  | ||   |   | |||         | | | ||  | |   |  ^***      
search RasMol script viewer Motif-ligand binding stats  MYRISTYL ..                | |             |  |    ||| | | |  ||  |      | ^*****   ^*****|              | | |                         |  | |      |  | | |       | |  | ^*****   | |||         | | | ||  | |   |            
search RasMol script viewer Motif-ligand binding stats  IG_MHC ..                | |             |  |    ||| | | |  ||  |      |  |         || ||              | | |                         |  | |      |  | | |       | |  |  |       | |||         | | | ||  **^****            
search RasMol script viewer Motif-ligand binding stats  betabulge ..                | |             |  |    **| | | |  ||  |      |  |         || ||              | | |                         |  | |      |  | | |       | |  |  |       | |||         | | | ||                     
search RasMol script viewer Motif-ligand binding stats  betabulgeloop ..                | |             |  |      | | | |  ||  |      |  |         || ||              | | |                         |  | |      |  | | |       | |  |  |       *****         | | | ||                     
search RasMol script viewer Motif-ligand binding stats  betaturn ..                | |             |  |      | | | ****|  |      |  |         ****|              | | |                         **** |      |  | | |       | |  |  |       ****|         | | | ||                     
search RasMol script viewer Motif-ligand binding stats  nest ..                | |             |  |      | | | |  ||  |      |  |          |  |              | | |                            ***      |  | | |       | |  |  |         ***         | | | ||                     
search RasMol script viewer Motif-ligand binding stats  niche ..                ***             ****      ***** ********      ****          ****              *** |                                     **** ***       ***  ****                     | | ****                     
search RasMol script viewer Motif-ligand binding stats  stmotif ..                                                                                                | |                                                                                  ***** |                      
search RasMol script viewer Motif-ligand binding stats  ststaple ..                                                                                                | |                                                                                    *****                      
search RasMol script viewer Motif-ligand binding stats  stturn ..                                                                                                ***                                                                                                               

chain N : PGT124 HEAVY CHAIN
JMol viewer RasMol script viewer  MAN 509A  ..                                                                                                      *                                            ..                                                                                 
JMol viewer RasMol script viewer  MAN 508A  ..                                                                                                      *                                            ..                                                                                 
JMol viewer RasMol script viewer  BMA 503A  ..                                                                                                      |*                                           ..                                                                                 
JMol viewer RasMol script viewer  NAG 502A  ..                                                                                                      |* ***                                       ..                                                                                 
JMol viewer RasMol script viewer  NAG 501A  ..                                                                                                      || |||                                       ..                                                                                 
JMol viewer RasMol script viewer  MAN 506A  ..                                                                                                     *|| |||                                       ..                                                                                 
sec str:  ....eeeee...ee.....eeeeeeee........eeeeee.....eeeeeee.....eee.hhhh..eeeeee....eeeeee...hhhhheeeeeeeeeeeeee........eeeeeeeeee...eeeee........eeeee........eeeeeeeeeee.....eeee.hhhh...eee...ee.....eeeeeeeeee.........eeeeee....eeeeee...
sequence :  ..QVQLQESGPGLVRPSETLSVTCIVSGGSISNYYWTWIRQSPGKGLEWIGYISDRETTTYNPSLNSRAVISRDTSKNQLSLQLRSVTTADTAIYFCATARRGQRIYGVVSFGEFFYYYYMDVWGKGTAVTVSSASTKGPSVFPLAPSS..GGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP
seq num:  ..1         11        21        31        41        51        61        71        81        88        98        100       102       112       140    ..151       161       171       181       191       201       211       221        
search RasMol script viewer Motif-ligand binding stats  PKC_PHOSPHO_SITE ..                         | |||||       |  |      | ^**||   |||||| |    |^** |    |  ||||||      ^**        || |||           |    |   ^**         ^*..|    |               | || |  |        | |||           | || | | |   |  | |  |     
search RasMol script viewer Motif-ligand binding stats  CK2_PHOSPHO_SITE ..                         | |||||       |  |      | ^***|   |||||| |    |  | |    |  |^***|                 |^***|           |    |                 ..|    |               | || |  |        | |||           | || | | |   |  | ^***     
search RasMol script viewer Motif-ligand binding stats  TYR_PHOSPHO_SITE ..                         | |||||       |  *******^ | | |   |||||| |    |  | |    |  ||||||                 |  | |           |    |                 ..|    |               | || |  |        | |||           | || | | |   |  |          
search RasMol script viewer Motif-ligand binding stats  MYRISTYL ..                         ^*****|       |  |        | | |   |||||| |    |  | |    |  ||||||                 |  | |           ^*****                 ..^*****               | |^*****        | |||           | || | | |   |  |          
search RasMol script viewer Motif-ligand binding stats  IG_MHC ..                           ||| |       |  |        | | |   |||||| |    |  | |    |  ||||||                 |  | |                                  ..                     | |  |           | |||           | || | **^****  |          
search RasMol script viewer Motif-ligand binding stats  asxturn ..                           ||| |       |  |        | | |   ***||| |    |  | |    |  ||||||                 |  | |                                  ..                     | |  |           | |||           | || |       |  |          
search RasMol script viewer Motif-ligand binding stats  betabulgeloop ..                           ||| |       |  |        | | |    | ||| |    ******    |  ||||||                 |  | |                                  ..                     | |  |           | |||           | || |       |  |          
search RasMol script viewer Motif-ligand binding stats  betaturn ..                           ||| |       |  |        | | |    ****| |       | |    |  |****|                 |  | |                                  ..                     | |  |           ****|           | || |       ****          
search RasMol script viewer Motif-ligand binding stats  gammaturn ..                           ||| |       |  |        | | |      | | |       | |    |  |||| |                 |  ***                                  ..                     | |  |             | |           | || |                     
search RasMol script viewer Motif-ligand binding stats  nest ..                           ||| |       |  |        | ***      *****       ***    |  |||| |                 |  |                                    ..                     | |  |             ***           | |***                     
search RasMol script viewer Motif-ligand binding stats  niche ..                           |****       ****        | |                           ****|****                 ****                                    ..                     ******             | |           ******                     
search RasMol script viewer Motif-ligand binding stats  stmotif ..                           | |                     | |                               *****                                                         ..                                        | |                                      
search RasMol script viewer Motif-ligand binding stats  stturn ..                           ***                     ***                               ***                                                           ..                                        ***                                      

chain A : SURFACE PROTEIN GP160
member of: GENE3D:searchG3DSA_2.170.40.20PFAM:searchPF00516SUPERFAMILY:searchSSF56502UniProt:searchP20871
JMol viewer RasMol script viewer  CL 521A  ..                                                                                                                                          ..    *                                                                                                             * *                                               
JMol viewer RasMol script viewer  NAG 520A  ..                                                                                                                                          ..    |                                                                                                             | |   *                                           
JMol viewer RasMol script viewer  NAG 519A  ..                                                                                                                                          ..    |                                                               *          *                                  | |   |                                           
JMol viewer RasMol script viewer  NAG 518A  ..                                                                                                                                          ..    |                                                         * *   |          |                                  | |   |                                           
JMol viewer RasMol script viewer  NAG 517A  ..                                                                                                                                          ..    |                      *    *                             | |   |          |                                  | |   |                                           
JMol viewer RasMol script viewer  NAG 516A  ..                                                                                                               *  *                       ..    |                      |    |                             | |   |          |                                  | |   |                                           
JMol viewer RasMol script viewer  NAG 515A  ..                                                                                         *      **             |  |                       ..    |                      |    |                             | |   |          |                                  | |***|                                           
JMol viewer RasMol script viewer  NAG 514A  ..                                                                                         |      ||             |  |                       ..    |                      |    |                             | |   |          |    *                             | |||||                                           
JMol viewer RasMol script viewer  NAG 513A  ..                                                                                         |      ||             |  |                       ..    |       **  *          |    |                             | |   |  *       |*   |                             | |||||                                           
JMol viewer RasMol script viewer  NAG 512A  ..                                                                                         |      ||             |  |                       ..    |       ||  |          |    |                             | |   |  |       ||   |                             | |||||                                           
JMol viewer RasMol script viewer  NAG 511A  ..                                                                                         |      ||             |  |               *       ..    |    *  ||  |          |    |                             | |   |  |       ||   |                             | |||||                                           
JMol viewer RasMol script viewer  MAN 508A  ..                                                                                         |      ||             |  |               |       ..    |    |  ||  |          |    |                             | |   |  |       ||   |                             | |||||                                           
JMol viewer RasMol script viewer  NAG 502A  ..                                                                                         |      ||             |  |               |       ..    |    |  ||  |          |    |                             | |   |  |       ||   |                             | |||||                                           
JMol viewer RasMol script viewer  NAG 501A  ..                                                                                         |      ||             |  |               *       ..    |  * *  ||  |          |    |                             | |   |  |       ||   |  *                          | |||||                                           
sec str:  ...ee.hhhhhhhhhhhhhhhhhhhhh...eee....eee....................eeeeee.......ee....eeee.............eee.........eee..........eeeeeeeeeeeeeee.............eeeeehhhhhhhhhhhhhhhhhhh...eeee......hhhhhheeeee..eeeee.......eee.............eeeeeeeee.eee......eee........eeeeeeeeeeeeee........eeeeee...hhhhhhhhhhh...eee.
sequence :  ..DFNMWKNNMVEQMQEDVINLWDQSLKPCVKLTGGSVITQACPKVSFEPIPIHYCAPAGFAILKCNNKTFNGKGQCKNVSTVQCTHGIRPVVSTQLLLNGSLAEEKVVIRSDNFTDNAKTIIVQLNESVKINCTRPSNN..IGDIRQAHCNISRAQWNNTLKQIVEKLREQFNNKTIVFTHSSGGDPEIVMHSFNCGGEFFYCNSTQLFNSTWNDTEKSSGTEGNDTIILPCRIKQIINMWQEVGKAMYAPPIKGQIRCSSNITGLLLTRDGGKNESEIEIFRPGGGDMRDNWRSELYKYKVVKI
seq num:  ..92        102       112       122       205       215       225       235       245       255       265       275       285       295     ..323       333       343       353       364       374       384       394       404       418       428       438       448       458       468       478       488 
search RasMol script viewer Motif-ligand binding stats  ASN_GLYCOSYLATION ..   |  | |            | |||       |    |                |  |    | ^***| ||   ^***            | || ^*** |        ^***  |      ^***| ^*** |^*..         ^***|  ^***|           ^***     |  | ||   |          ^***  ^***^***| || | ^***           |  |           |    | ^***    |    ^***||       | |  || ||  |     
search RasMol script viewer Motif-ligand binding stats  PKC_PHOSPHO_SITE ..   |  | |            | ^**       |    |                |  |    | |   | ||    |              | ||  ||  |        |  |  |        ^**    | |  ..           | |    ^**                    |  | ||   |                  |  |^** || |  |             |  |           |    |    |    |    ||||||       | |  || ||  |     
search RasMol script viewer Motif-ligand binding stats  CK2_PHOSPHO_SITE ..   |  | |            |  |        |    |                |  |    | |   | ||    |              | ||  |^***        |  |  |               | |  ..           | |                           ^*** ||   |                  ^***  | ^***  |             |  |           |    |    |    |    ||^***       | |  || ||  |     
search RasMol script viewer Motif-ligand binding stats  MYRISTYL ..   |  | |            |  |        ^*****                |  |    | |   | |^*****              | ||  |            |  |  |               | |  ..           | |                              | ||   |                     |  |  ^*****             |  |           ^*****    ^*****    |||||        | |  || ||  |     
search RasMol script viewer Motif-ligand binding stats  alphabetamotif ..   |  | |            |  |                              |  |    | |   | |                    | ||  |            |  |  |               | |  ..           | |                              | ||   |                     |  |                     |  |                               |||||        | ********  |     
search RasMol script viewer Motif-ligand binding stats  asxturn ..   |  ***            |  |                              |  |    | |   | |                    | ||  |            |  |  |               | |  ..           | |                              | ||   |                     |  |                     |  |                               |||||        ***  |  ||  |     
search RasMol script viewer Motif-ligand binding stats  betaturn ..   |  |              |  |                              ****    | |   | |                    | ||  |            |  |  |               | |  ..           | |                              ****   |                     |  |                     |  |                               |||||          *******|  |     
search RasMol script viewer Motif-ligand binding stats  gammaturn ..   |  |              |  |                              |  |    | |   | |                    ***|  |            |  |  |               | |  ..           | |                                |    |                     |  |                     |  |                               |||||                 |  |     
search RasMol script viewer Motif-ligand binding stats  nest ..   |  |              |  |                              |  |    | |   ***                       |  |            |  |  |               | |  ..           | |                                |    |                     |  |                     |  |                               *****                 |  |     
search RasMol script viewer Motif-ligand binding stats  niche ..   ****              ****                              ****    ***                             ****            *******               ***  ..           | |                                |    |                     ****                     ****                                                     ****     
search RasMol script viewer Motif-ligand binding stats  ststaple ..                                                                                                                                          ..           | |                                ******                                                                                                                
search RasMol script viewer Motif-ligand binding stats  stturn ..                                                                                                                                          ..           ***                                                                                                                                                      

   New search    4r2g:  Sequences  |  3D motifs  |  Ligand environment  |   Ligand bonds   |  SPICE view  |  PDB  |  XML  |  Structure factors