triangle PDBeMotif: 3se4  
  coner Sequences coner   coner 3D motifs coner   coner Ligand environment coner   coner Ligand bonds coner
   
coner
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coner
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Classification immune system receptor    | release date: Fri, Jun 10, 2011
Title human ifnw-ifnar ternary complex
Authors C.THOMAS, K.C.GARCIA
Method X-RAY DIFFRACTION (resolution: 3.50Å)
PDBe Citation   
Small molecules:    search NAG NAG binding statistics NAG
Modified residues:  search ASN ASN binding statistics ASN
Ligand bond colours:   *  covalent   *  ionic   *  hydrogen   *  electrostatic   *  van-der-waals   *  plane-atom   *  plane-plane   *  undefined  - Click here to show 5Å bonds
Chain A sequence:
ADLGSKNLKSPQKVEVDIIDDNFILRWNRSDESVGNVTFSFDYQKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKL
RIRAEKENTSSWYEVDSFTPFRKAQIGPPEVHLEAEDKAIVIHISPGTKDSVMWALDGLSFTYSLVIWKNSSGVEERIEN
IYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQNQNYVLKWDYTYANMTFQVQWL
HAFLKRNPGNHLYKWKQIPDCENVKTTQCVFPQNVFQKGIYLLRVQASDGNNTSFWSEEIKFDTEIQAFLLPPVFNIRSL
SDSFHIYIGAPKQSGNTPVIQDYPLIYEIIFWENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHTMDEKLNKSSVFS
DAVCEKTKPGNTSK
Chain B sequence:
ADPLGCDLPQNHGLLSRNTLVLLHQMRRISPFLCLKDRRDFRFPQEMVKGSQLQKAHVMSVLHEMLQQIFSLFHTERSSA
AWQMTLLDQLHTGLHQQLQHLETCLLQVVGEGESAGAISSPALTLRRYFQGIRVYLKEKKYSDCAWEVVRMEIMKSLFLS
TNMQERLRSKDRDLGSS
Chain C sequence:
YTDESCTFKISLRNFRSILSWELKNHSIVPTHYTLLYTIMSKPEDLKVVKNCANTTRSFCDLTDEWRSTHEAYVTVLEGF
SGNTTLFSCSHNFWLAIDMSFEPPEFEIVGFTNHINVMVKFPSIVEEELQFDLSLVIEEQSEGIVKKHKPEIKGNMSGNF
TYIIDKLIPNTNYCVSVYLEHSDEQAVIKSPLKCTLLPP
Residue colours:  hydrophilic   hydrophobic   intermediate 
Assembly 1     View the assembly/model: ( JMolViewer Download PDB file RasMol script viewer AstexViewer™@MSD-EBI )
Motif search   chain:    Sequence numbers: 
   Using:   φ/ψ    residues code    secondary structures   
 coordinates of:  Cαs Side-chain
 
      View the fragment: rasmol script JMol viewer
chain A : INTERFERON ALPHA/BETA RECEPTOR 1
JMol viewer RasMol script viewer  NAG 410A  ..                ..                                                                                                                 *                                                                                                    ..NAG ..                                                       
sec str:  .......eeee..eeee....eeeeeeee......eeeeeeeee....ee...........eeeeeeeee..eeeeee....hhhhhh.....eeeeee....eeeeee........hhhhhh..eeeeeeee.....eeeeeee..eeee.......eeeeeeeee......eeee...eeee..........eeeeeeee..eeeeeee......eeeeeeee.hhhh....... .................eeeee.hhh...eeeeeeeee....eeee...eeee....
sequence :  ..PQKVEVDIIDDNFILR..VTFSFDYQKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRAEKENTSSWYEVDSFTPFRKAQIGPPEVHLEAEDKAIVIHISPGTKDSVMWALDGLSFTYSLVIWKNSSGVEERIENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQNQNYVLKWDYTYANMTFQVQWLHAFLKRNPGN... ..YKWKQIPDCENVKTTQCVFPQNVFQKGIYLLRVQASDGNNTSFWSEEIKFDTEIQ
seq num:  ..6         16    ..32        42        52        62        72        82        92        102       112       122       132       142       152       162       172       182       192       202       212       222       232       242 ... ..248       258       268       278       288       298  
search RasMol script viewer Motif-ligand binding stats  PS00001 ..        || |    ..***     || ||      |||^*** | ^*** | | ||         | ^***  |    | | ||                      ||  ||     || | |      ^***||  |  |       | |  | |          | |           |  || |          |  |          ^***       || ||   ..PS00001..      | || |                        ||^***|            
search RasMol script viewer Motif-ligand binding stats  PS00005 ..        || |    ..        || ||      ||| | ^** | |^** | ||         |  | |  |    | | ||                      ||  ||     || | |        | ||  |  |       | |  | |          ^**           |  || |          |  |                     || ||   ..PS00005..      | || |                        ||||  |            
search RasMol script viewer Motif-ligand binding stats  PS00006 ..        || |    ..        |^***      ||| | | | | |    | ||         |  | ^***    | | ||                      ||  ||     || | |        ^***  |  |       | |  | |          | |           ^***| |          |  |                     || ||   ..PS00006..      | || |                        ||||  |            
search RasMol script viewer Motif-ligand binding stats  PS00007 ..        || |    ..        |  |       ||| | | | | |    | ||         |  |         | | ||                      ||  ||     || | |        | |   |  |       *******^          | |               | |          |  |                     || ||   ..PS00007..      | || |                        ||||  |            
search RasMol script viewer Motif-ligand binding stats  PS00008 ..        || |    ..        |  |       ||| | | | | |    | ||         |  |         | | ||                      ^*****     ^*****        | |   |  |         |  |            | |               | |          |  |                     || ||   ..PS00008..      | || |                        |^*****            
search RasMol script viewer Motif-ligand binding stats  asxturn ..        || |    ..        |  |       ||| | | | ***    | ||         |  |         | | ||                       |  |       | |          | |   |  |         |  |            | |               ***          |  |                     || ||   ..asxturn..      | || |                        ***|               
search RasMol script viewer Motif-ligand binding stats  betaturn ..        ****    ..        |  |       ||| | | |        ****         ****         | | ||                       |  |       | |          | |   |  |         |  |            | |               | |          ****                     ****|   ..betaturn..      **** |                        ||||               
search RasMol script viewer Motif-ligand binding stats  nest ..         | |    ..        |  |       *** | | |        ***|                      | | ||                       |  |       | |          ***   |  |         |  |            ***               | |                                    |  |   ..nest..      | || |                        ****               
search RasMol script viewer Motif-ligand binding stats  niche ..         ***    ..        ****        ********        ****                      | ****                       ****       ***                ****         ****                              ***                                    ****   ..niche..      ******                                           
search RasMol script viewer Motif-ligand binding stats  stmotif ..                ..                                                              *****                                                                                                                                                   ..stmotif..                                                       

chain B : INTERFERON OMEGA-1
sec str:  .........hhhhhhhhhhhhhhh...hhhhhh...............hhhhhhhhhhhhhhhhhhhhh..hhhhh.hhhhhhhhhhhhhhhhhhhh.......hhhhhhhhhhhhhhhhhhhhh.hhhhhhhhhhhhhhhhhhhh...
sequence :  ..GCDLPQNHGLLSRNTLVLLHQMRRISPFLCLKDRRDFRFPQEMV..QKAHVMSVLHEMLQQIFSLFHTERSSAAWQMTLLDQLHTGLHQQLQHLETCLLQ..SPALTLRRYFQGIRVYLKEKKYSDCAWEVVRMEIMKSLFLSTNMQ
seq num:  ..2         12        22        32        42  ..51        61        71        81        91        101 ..117       127       137       147       157  
search RasMol script viewer Motif-ligand binding stats  PS00004 ..       |  |        |  **^*    |  | |||| | | ..                  || | ||||||  |  |          | | || | ..    | | |          **^* | |     |   | |||||| 
search RasMol script viewer Motif-ligand binding stats  PS00005 ..       |  |        |  |       |  | |||| | | ..                  || ^**|||||  |  |          | | || | ..    ^** |          | |  | |     |   | |||||| 
search RasMol script viewer Motif-ligand binding stats  PS00006 ..       |  |        |  |       |  | |||| | | ..                  || | ||||||  ^***          | | || | ..        |          | |  | |     |   | |||||| 
search RasMol script viewer Motif-ligand binding stats  PS00252 ..       |  |        |  |       |  | |||| | | ..                  || | ||||||                | | || | ..        ****************^**     |   | |||||| 
search RasMol script viewer Motif-ligand binding stats  alphabetamotif ..       |  |        |  |       |  | |||| | | ..                  || | ||||||                | | || | ..                   | |          |   | *****| 
search RasMol script viewer Motif-ligand binding stats  asxturn ..       |  |        |  |       |  | ***| | | ..                  || | ||||||                | | || | ..                   | |          |   | |||||| 
search RasMol script viewer Motif-ligand binding stats  betaturn ..       ****        ****       |  |  | | | | ..                  || | *****|                | **** | ..                   | |          |   | ****** 
search RasMol script viewer Motif-ligand binding stats  gammaturn ..                   |  |       |  |  | *** | ..                  || |  ||  |                |   || | ..                   | |          |   |   |  | 
search RasMol script viewer Motif-ligand binding stats  nest ..                   |  |       |  |  *** | | ..                  || |  ||  |                |   || | ..                   ***          |   |   |  | 
search RasMol script viewer Motif-ligand binding stats  niche ..                   ****       ****      *** ..                  ****  |****                |   |*** ..                                |   |   **** 
search RasMol script viewer Motif-ligand binding stats  ststaple ..                                            ..                   ******                    *****    ..                                *****        

chain C : INTERFERON ALPHA/BETA RECEPTOR 2
sec str:  ....eeeeeeeee..eeeeeeeee.......eeeeeeee.......ee..........ee...........eeeeeeeee....eeeeeeeeeehhhhhee...eee.......eeeeee...........eeeeeee....eeee.........eeeeee.......eeeeeeeee............eeee...
sequence :  ..DESCTFKISLRNFRSILSWELKNHSIVPTHYTLLYTIMSKPEDLKVVKNCANTTRSFCDLTDEWRSTHEAYVTVLEGFSGNTTLFSCSHNFWLAIDMSFEPPEFEIVGFTNHINVMVKFPSI..LQFDLSLVIEEQSEGIVKKHKPEI..MSGNFTYIIDKLIPNTNYCVSVYLEHSDEQAVIKSPLKCTLLPP
seq num:  ..9         19        29        39        49        59        69        79        89        99        109       119         ..135       145       155 ..162       172       182       192       202 
search RasMol script viewer Motif-ligand binding stats  PS00001 ..    | | | |  |        ^***            || |     |  |^***|  | |  | |  |   |  |    ^***       |  |||                       | ..            |  |        ..***^*** |  ||  |          | |               
search RasMol script viewer Motif-ligand binding stats  PS00005 ..    ^** ^**  |                        || |     |  | ^**|  | |  | |  |   |  |               |  |||                       | ..            |  |        ..   |    |  ||  |          | |               
search RasMol script viewer Motif-ligand binding stats  PS00006 ..          |  |                        ^***     |  | | |^*** |  | ^***   ^***               |  |||                       ^*..            |  |        ..   |    |  ||  |          | |               
search RasMol script viewer Motif-ligand binding stats  PS00008 ..          |  |                         | |     |  | | |   | |  | |  |                      |  |||                         ..            |  |        ..****    |  ||  |          | |               
search RasMol script viewer Motif-ligand binding stats  alphabetamotif ..          |  |                         | |     |  | | |   | |  | |  |                      *****|                         ..            |  |        ..        |  ||  |          | |               
search RasMol script viewer Motif-ligand binding stats  asxturn ..          |  |                         | |     |  | | |   ***  | |  |                      |  | |                         ..            |  |        ..        |  ||  |          | |               
search RasMol script viewer Motif-ligand binding stats  betaturn ..          ****                         | |     |  | | |        | |  |                      **** |                         ..            |  |        ..        |  ||  |          | |               
search RasMol script viewer Motif-ligand binding stats  gammaturn ..                                       ***     |  | | |        | |  |                         | |                         ..            |  |        ..        |  ||  |          | |               
search RasMol script viewer Motif-ligand binding stats  niche ..                                               **** ***        ******                         ***                         ..            ****        ..        ********          | |               
search RasMol script viewer Motif-ligand binding stats  stturn ..                                                    ***                                                                   ..                        ..                          ***               

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