triangle PDBeMotif: 3rk9  
  coner Sequences coner   coner 3D motifs coner   coner Ligand environment coner   coner Ligand bonds coner
   
coner
   Search  |  PDB header search  |  Upload PDB file  |  Molecule binding  |  Pair bonds  |  Motif binding  |  3D environment  |  Motif inclusion  
coner
AstexViewer TM
Download original PDB file
Download xml file
Download structure factors file
Enzyme   2.7.11.22
Classification transferase/transferase inhibitor    | release date: Sun, Apr 17, 2011
Title cdk2 in complex with inhibitor rc-2-74
Authors A.BECKER, E.SCHONBRUNN, H.HAN, R.ALAM, S.BETZI
Method X-RAY DIFFRACTION (resolution: 1.85Å)
PDBe Citation   
Small molecules:    search 09Z 09Z binding statistics 09Z
Ligand bond colours:   *  covalent   *  ionic   *  hydrogen   *  electrostatic   *  van-der-waals   *  plane-atom   *  plane-plane   *  undefined  - Click here to show 5Å bonds
Chain A sequence:
GPLGSPEFMENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHT
ENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAF
GVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTS
MPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
Residue colours:  hydrophilic   hydrophobic   intermediate 
Assembly 1     View the assembly/model: ( JMolViewer Download PDB file RasMol script viewer AstexViewer™@MSD-EBI )
Motif search   chain:    Sequence numbers: 
   Using:   φ/ψ    residues code    secondary structures   
 coordinates of:  Cαs Side-chain
 
      View the fragment: rasmol script JMol viewer
chain A : CYCLIN-DEPENDENT KINASE 2
member of: CATH:search1.10.510.10/search3.30.200.20GENE3D:searchG3DSA_1.10.510.10/searchG3DSA_3.30.200.20PANTHER:searchPTHR24056/searchPTHR24056_SF168PFAM:searchPF00069PROSITE PATTERNS:searchPS00107/searchPS00108, PROSITE PROFILES:searchPS50011, SMART:searchSM00220SUPERFAMILY:searchSSF56112UniProt:searchP24941
JMol viewer RasMol script viewer  09Z 483A  ..         *       *            * *   ..                       *                *** *                                              * *          *                                                                                                                                                         
sec str:  .....eeeeeeee....eeeeeeee.....eeeeeee.........hhhhhhhhhhh........eeeeeee..eeeeeee...eehhhhhhhh.....hhhhhhhhhhhhhhhhhhhhhh.......hhh.eee.....eee..........................hhhhhh......hhhhhhhhhhhhhhhhhh.......hhhhhhhhhhhhhh........hhhhh.............hhhhhh...hhhhhhhhhhhh........hhhhhhhhhhhh...........
sequence :  ..MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR..TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
seq num:  ..1         11        21        31    ..41        51        61        71        81        91        101       111       121       131       141       151       161       171       181       191       201       211       221       231       241       251       261       271       281       291     
search RasMol script viewer Motif-ligand binding stats  CAMP_PHOSPHO_SITE ..|  |    ||    |       | ||||    |   .. ||   || |||  || | |  |   ||                 | |                         |    ||||| | | || || |  | |      |    |            ||  |     | | | |||||  | |   ||  | |      |  |   |   |  |  |  | ||||| |||  |      | |      | |      |  | || **^* | |  || || |         
search RasMol script viewer Motif-ligand binding stats  PKC_PHOSPHO_SITE ..|  |    ||    |       | ||||    |   .. ||   || |||  || | |  |   ||                 | |                         |    |^**| | | || || |  | |      |    |            ||  |     | | | |||||  | |   ||  ^**      |  |   |   |  |  |  | ||||| |||  |      | |      | |      |  | || || ^** |  || || |         
search RasMol script viewer Motif-ligand binding stats  CK2_PHOSPHO_SITE ..|  |    ||    |       | ||||    |   ..**|   || |||  || | |  |   ||                 | |                         |    | ||| | | || || |  | |      |    |            ||  |     | | | |^***  | |   ||  | |      ^***   |   |  ^***  | |||^***||  |      | |      | |      |  | || || |   |  || || |         
search RasMol script viewer Motif-ligand binding stats  TYR_PHOSPHO_SITE ..|  |    ******^       | ||||    |   ..  |   || |||  || | |  |   ||                 | |                         |    | ||| | | || || |  | |      |    |            ||  |     | | | | ||   | |   ||  | |             |   |        | ||| |  ||  |      | |      | |      |  | || || |   |  || || |         
search RasMol script viewer Motif-ligand binding stats  MYRISTYL ..|  |     |            | ||||    |   ..  ^***** |||  || | |  |   ||                 | |                         ^***** ||| | | || || |  | |      ^*****            ||  |     | | | | ||   | ^*****  | |             |   |        | ||| |  ||  |      | |      | |      |  | || || |   |  || || |         
search RasMol script viewer Motif-ligand binding stats  PROTEIN_KINASE_ATP ..|  |     ************************   ..      || |||  || | |  |   ||                 | |                              | ||| | | || || |  | |                        ||  |     | | | | ||   |     |   | |             |   |        | ||| |  ||  |      | |      | |      |  | || || |   |  || || |         
search RasMol script viewer Motif-ligand binding stats  PROTEIN_KINASE_ST ..|  |                  | ||||        ..      || |||  || | |  |   ||                 | |                              | ||****^********  | |                        ||  |     | | | | ||   |     |   | |             |   |        | ||| |  ||  |      | |      | |      |  | || || |   |  || || |         
search RasMol script viewer Motif-ligand binding stats  alphabetamotif ..|  |                  | ||||        ..      ********** | |  |   ||                 | |                              | ||| | | || ||    | |                        ||  |     | | | | ||   |     |   | |             |   |        | ||| |  ||  |      | |      | |      |  | ***** |   |  || || |         
search RasMol script viewer Motif-ligand binding stats  asxmotif ..|  |                  *****|        ..      || |||  |  | |  |   ||                 | |                              | ||| | | || ||    | |                        ||  |     | | | | ||   |     |   | |             |   |        | ||| |  ||  |      | |      | |      |  | || || |   |  || || |         
search RasMol script viewer Motif-ligand binding stats  asxturn ..|  |                  ***| |        ..      || |||  |  | |  |   ||                 ***                              | ||| | | || ||    | |                        ||  |     | | | | ||   |     |   | |             |   |        | ||| |  ||  |      ***      ***      |  | || || |   |  || || |         
search RasMol script viewer Motif-ligand binding stats  betabulge ..|  |                  |  | |        ..      || |||  |  | |  |   **                                                  | ||| | | || ||    | |                        ||  |     | | | | ||   |     |   | |             |   |        | ||| |  ||  |                        |  | || || |   |  || || |         
search RasMol script viewer Motif-ligand binding stats  betabulgeloop ..|  |                  ******        ..      || |||  |  | |  |                                                       | ||| | | || ||    | |                        ||  |     | | | | ||   |     |   | |             |   |        | ||| |  ||  |                        |  | || || |   |  || || |         
search RasMol script viewer Motif-ligand binding stats  betaturn ..|  |                     | |        ..      ************ |  |                                                       ****| | | ****|    | |                        ||  |     | | | | ||   |     |   | |             |   |        ****| |  ||  |                        |  | ****| |   ******** |         
search RasMol script viewer Motif-ligand binding stats  nest ..|  |                     ***        ..                   |  |                                                         *** *** || ||    ***                        ||  |     *** | | ||   |     |   ***             |   |          *** |  ||  |                        |  | ||  | |   |  |  |  |         
search RasMol script viewer Motif-ligand binding stats  niche ..****                                ..                   ****                                                               | |****                               |****       *** | ||   |     |   |               |   |           ***********                        ********** |   ****  ****         
search RasMol script viewer Motif-ligand binding stats  stmotif ..                                    ..                                                                                      | |  |                                |               | ||   |     |   |               |   |                                                         *****                  
search RasMol script viewer Motif-ligand binding stats  ststaple ..                                    ..                                                                                      | |  |                                |               | |*****     *****               *****                                                                                
search RasMol script viewer Motif-ligand binding stats  stturn ..                                    ..                                                                                      | |  |                                |               ***                                                                                                                   
search RasMol script viewer Motif-ligand binding stats  Catalytic site ..                                    ..                                                                                      * *  *                                *                                                                                                                                     

   New search    3rk9:  Sequences  |  3D motifs  |  Ligand environment  |   Ligand bonds   |  SPICE view  |  PDB  |  XML  |  Structure factors