3gjn: Sequences

PDBeMotif: 3gjn

		Sequences				3D motifs				Ligand environment				Ligand bonds

Help About

Enzyme:	3.1.
Classification:	hydrolase \| release date: Mon, Mar 9, 2009
Title:	following evolutionary paths to high affinity and selectivit protein interactions using colicin7 and immunity proteins
Authors:	D.S.TAWFIK, O.DYM
Method:	X-RAY DIFFRACTION (resolution: 2.48Å)

PDBe Citation

Small molecules:

Ligand bond colours:

covalent

ionic

hydrogen

electrostatic

van-der-waals

plane-atom

plane-plane

undefined

- Click here to show 5Å bonds

Chains A,D sequence:
MELKHSISDYTEAEFLQLVTTICDAEATSEEELDKLITHFEEMTEHPSGSDLIYWPKEGDDDSPSGIVNTVKQWRAANGK
SGFKQG

Chains B,C sequence:
MHHHHHHSMGKRNKPGKATGKGKPVNNKWLNNAGKDLGSPVPDRIANKLRDKEFKSFDDFRKKFWEEVSKDPELSKQFSR
NNNDRMKVGKAPKTRTQDVSGKRTSFELHAEKPISQNGGVYDMDNISVVTPKRHIDIHRGK

Residue colours: hydrophilic hydrophobic intermediate

Assembly 1

View the assembly/model: (

)

Motif search

chain:

Sequence numbers:

Using:	φ/ψ residues code secondary structures
	coordinates of: Cαs Side-chain

View the fragment:

chain A : COLICIN-E9 IMMUNITY PROTEIN member of: CATH:1.10.1200.20, GENE3D:G3DSA_1.10.1200.20, PFAM:PF01320, PRINTS:PYOCIN, PRODOM:PD007225, SUPERFAMILY:SSF47345, UniProt:P13479
`sec str:`	`....hhhhhhhhhhhhhhhhhh.....hhhhhhhhhhhhhhhhh....hhhhhh.......hhhhhhhhhhhhhhhh.......`
`sequence :`	`..KHSISDYTEAEFLQLVTTICDAEATSEEELDKLITHFEEMTEHPSGSDLIYWPKEGDDDSPSGIVNTVKQWRAANGKSGFKQ`
`seq num:`	`..1004 1014 1024 1034 1044 1054 1064 1074`
`PKC_PHOSPHO_SITE`	`.. \|\| \|\|\| \|\| \| \| \| \| \| \| \|\|\|\|\|\|\| \| \| \|\| \|\| \| \|\| \|\| \|\|\| ^** \| \|`
`CK2_PHOSPHO_SITE`	`.. ^*\|^\| ^ \| ^* \| ^*\|\|\| \| ^* \|\| \| \|\| \|\| \|\|\| \|\| \| \|`
`MYRISTYL`	`.. \| \|\| \| \| \| \| \|\|\| \|\|\| \| \| \|\| \|\| \| \|\| \|\| ^***** \| \|`
`alphabetamotif`	`.. \| \|\| \| \| \| \| \|***\| \| \| * \| \|\| \|*** \| \| \|`
`betaturn`	`.. **\| \| \| \| \| \| \| \| ** \| \|** \| \| \|`
`nest`	`.. \| \|\| \| * \| \| \| * \| \|\| \| \|\| \| ***`
`niche`	`.. **\| \| \| \| \| \| \| ***** \|\| \|`
`stmotif`	`.. *** \| \| \| \| \| *** \|`
`ststaple`	`.. *** * \| ***`
`stturn`	`.. ***`

Assembly 2

View the assembly/model: (

)

Motif search

chain:

Sequence numbers:

Using:	φ/ψ residues code secondary structures
	coordinates of: Cαs Side-chain

View the fragment:

chain B : COLICIN-E7 member of: CATH:3.90.540.10, GENE3D:G3DSA_1.10.287.620/G3DSA_3.90.540.10, PFAM:PF11570/PF12639, SMART:SM00507, SUPERFAMILY:SSF54060/SSF69985, UniProt:Q47112
`ZN` `600B`	`.. * .. * *`
`sec str:`	`...ee........hhhhhh.....ee.hhhhhhhhh.....hhhhhhhhhhhhhh.hhhhhh..hhhhhhhhhh......hhhhh.......eeee......ee...eeeehhhhhhhhhh..`
`sequence :`	`..KATGKGKPVNNKWLNNAGKDLGSPVPDRIANKLRDKEFKSFDDFRKKFWEEVSKDPELSKQFSRNNNDRMKVGKAPKTRTQDVSGKRTSFELHAEKP..VYDMDNISVVTPKRHIDIHRGK`
`seq num:`	`..452 462 472 482 492 502 512 522 532 542 ..555 565`
`ASN_GLYCOSYLATION`	`.. \| \| \| \| \| \| \| \| \| \|\|\| \|\|\| \| \| \|\|\| \| \|\| \|\|\|\| \| \|\| .. \|\|\|^*** \| \| \| \|`
`CAMP_PHOSPHO_SITE`	`.. \| \| \| \| \| \| \| \| \| \|\|\| \|\|\| \| \| \|\|\| \| \|\| *^ \| \|\| .. \|\|\| \| \| \| \| \|`
`PKC_PHOSPHO_SITE`	`.. ^ \| \| \| \| \| \| \| \|\|\| \|\|\| \| \| \|\|\| \| \|^\|\|\| \| \|\| .. \|\|\| \| ^** \| \|`
`CK2_PHOSPHO_SITE`	`.. \| \| \| ^* \| \| \|\|\| \|\|\| \| \| \|\|\| \| \|\| \|^* \|\| .. \|\|\| \| \| \|`
`AMIDATION`	`.. \| \| \| \| \| \|\|\| \|\|\| \| \| \|\|\| \| \|^*** \| \| \|\| .. \|\|\| \| \| \|`
`alphabetamotif`	`.. \| \| \| \| ***** \|\|\| \| \| \|\|\| \| \| \| \| \| \|\| .. \|\|\| \| \| \|`
`asxmotif`	`.. \| \| \| \| ***** \|\|\| \| \| \|\|\| \| \| \| \| \| \|\| .. \|\|\| \| \| \|`
`asxturn`	`.. \| \| \| \| *\|\| \|\|\| \| \| \|\|\| \| \| \| \| \| \|\| .. * \| \| \|`
`betaturn`	`.. \| ** \| ***\|\| \| **\| \| \| \| \| \| \|\| .. \| \| \| \|`
`nest`	`.. \| \| \| \| \| \|\| \| * \| \| \| \| \| \|\| .. \| \| *`
`niche`	`.. ** \| \| * \| \|\| .. ****`
`stmotif`	`.. ***** \| \|\| ..`
`Catalytic site`	`.. * ** ..`

chain D : COLICIN-E9 IMMUNITY PROTEIN member of: CATH:1.10.1200.20, GENE3D:G3DSA_1.10.1200.20, PFAM:PF01320, PRINTS:PYOCIN, PRODOM:PD007225, SUPERFAMILY:SSF47345, UniProt:P13479
`sec str:`	`....hhhhhhhhhhhhhhhhhh.....hhhhhhhhhhhhhhhhh....hhhhhh.......hhhhhhhhhhhhhhhh.......`
`sequence :`	`..KHSISDYTEAEFLQLVTTICDAEATSEEELDKLITHFEEMTEHPSGSDLIYWPKEGDDDSPSGIVNTVKQWRAANGKSGFKQ`
`seq num:`	`..1004 1014 1024 1034 1044 1054 1064 1074`
`PKC_PHOSPHO_SITE`	`.. \|\|\|\|\|\| \|\| \| \| \| \| \| \| \| \|\| \| \| \|\|\|\| \|\| \| \|\| \| \|\| ^** \| \| \|`
`CK2_PHOSPHO_SITE`	`.. ^*\|^\| ^ \| ^* \| ^* \| \| ^* \|\| \| \|\| \| \|\| \|\| \| \| \|`
`MYRISTYL`	`.. \|\|\|\|\|\| \| \| \| \| \| \| \| \| \| \| \|\|\|\| \|\| \| \|\| \| ^***** \| \| \|`
`alphabetamotif`	`.. \|\|\|\|\|\| \| \| \| \| \| \| \| \| \| \| \|\|*** \| \|\| *** \| \| \| \|`
`asxturn`	`.. \|\|\|\|\|\| \| \| \| \| \| \| \| \| \| \| \|\|\|\| \| \| \|*** \|\| \| \| \| \|`
`betaturn`	`.. ***\| \| \| \| \| \| \| \| **** \| \| \| ** \|`
`nest`	`.. \|\|\| \|\| \| \| \| * \| \| \| * \| \|\| \| \|\| \| ***`
`niche`	`.. \|**\| \| \| \| \| \| ***** \|\| \|`
`stmotif`	`.. ******** \| \| \| \| *** \|`
`ststaple`	`.. \| \| *** * ***`
`stturn`	`.. ***`

Assembly 3

View the assembly/model: (

)

Motif search

chain:

Sequence numbers:

Using:	φ/ψ residues code secondary structures
	coordinates of: Cαs Side-chain

View the fragment:

chain C : COLICIN-E7 member of: CATH:3.90.540.10, GENE3D:G3DSA_1.10.287.620/G3DSA_3.90.540.10, PFAM:PF11570/PF12639, SMART:SM00507, SUPERFAMILY:SSF54060/SSF69985, UniProt:Q47112
`ZN` `600C`	`.. * .. * *`
`sec str:`	`.....ee........hhhhhhhh...ee.hhhhhhhhh.....hhhhhhhhhhhhhhhhhhhhh..hhhhhhhhhh......hhhhh.......eeee.....ee...eeeehhhhhhhhhh..`
`sequence :`	`..PGKATGKGKPVNNKWLNNAGKDLGSPVPDRIANKLRDKEFKSFDDFRKKFWEEVSKDPELSKQFSRNNNDRMKVGKAPKTRTQDVSGKRTSFELHAEK..VYDMDNISVVTPKRHIDIHRGK`
`seq num:`	`..450 460 470 480 490 500 510 520 530 540 ..555 565`
`ASN_GLYCOSYLATION`	`.. \| \| \| \| \| \| \| \| \| \| \|\| \|\| \| \|\|\| \|\| \|\| \|\| \|\|\| \| \|\| \|\|\|\| \| \|\| .. \|\|\|^*** \| \| \| \| \|`
`CAMP_PHOSPHO_SITE`	`.. \| \| \| \| \| \| \| \| \| \| \|\| \|\| \| \|\|\| \|\| \|\| \|\| \|\|\| \| \|\| *^ \| \|\| .. \|\|\|\|\| \| \| \| \| \|`
`PKC_PHOSPHO_SITE`	`.. ^ \| \| \| \| \| \| \| \| \|\| \|\| \| \|\|\| \|\| \|\| \|\| \|\|\| \| \|^\|\| \| \|\| .. \|\|\|\|\| ^** \| \| \|`
`CK2_PHOSPHO_SITE`	`.. \| \| \| \| \| ^* \| \|\| \|\| \| \|\|\| \|\| \|\| \|\| \|\|\| \| \|\| \|^* \|\| .. \|\|\|\|\| \| \| \| \|`
`AMIDATION`	`.. \| \| \| \| \| \| \|\| \|\| \| \|\|\| \|\| \|\| \|\| \|\|\| \| \|^*** \| \|\| .. \|\|\|\|\| \| \| \| \|`
`alphabetamotif`	`.. \| \| \| \| \| ******** \| \|\|\| \|\| \|\| \|\| \|\|\| \| \| \| \|\| .. \|\|\|\|\| \| \| \| \|`
`asxmotif`	`.. \| \| \| \| \| \| \| \| *** \|\| \|\| \|\| \|\|\| \| \| \| \|\| .. *** \| \| \| \|`
`asxturn`	`.. \| \| \| \| \| \| \| \| *\|\| \|\| \|\| \|\| \|\|\| \| \| \| \|\| .. *\|\| \| \| \| \|`
`betaturn`	`.. \| ** *** \| \|\| ****\| \| \| \| \|\| .. **\| \| \| \| \|`
`nest`	`.. \| \| \| \| \| \|\| \| * \| \| \| \|\| .. \| \| \| \| *`
`niche`	`.. ** \| \| \| \|\| .. ** \| \|`
`stmotif`	`.. *** \| \|\| .. ***`
`Catalytic site`	`.. * ** ..`

Assembly 4

View the assembly/model: (

)

Motif search

chain:

Sequence numbers:

Using:	φ/ψ residues code secondary structures
	coordinates of: Cαs Side-chain

View the fragment:

chain D : COLICIN-E9 IMMUNITY PROTEIN member of: CATH:1.10.1200.20, GENE3D:G3DSA_1.10.1200.20, PFAM:PF01320, PRINTS:PYOCIN, PRODOM:PD007225, SUPERFAMILY:SSF47345, UniProt:P13479
`sec str:`	`....hhhhhhhhhhhhhhhhhh.....hhhhhhhhhhhhhhhhh....hhhhhh.......hhhhhhhhhhhhhhhh.......`
`sequence :`	`..KHSISDYTEAEFLQLVTTICDAEATSEEELDKLITHFEEMTEHPSGSDLIYWPKEGDDDSPSGIVNTVKQWRAANGKSGFKQ`
`seq num:`	`..1004 1014 1024 1034 1044 1054 1064 1074`
`PKC_PHOSPHO_SITE`	`.. \|\|\|\|\|\| \|\| \| \| \| \| \| \| \| \|\| \| \| \|\|\|\| \|\| \| \|\| \| \|\| ^** \| \| \|`
`CK2_PHOSPHO_SITE`	`.. ^*\|^\| ^ \| ^* \| ^* \| \| ^* \|\| \| \|\| \| \|\| \|\| \| \| \|`
`MYRISTYL`	`.. \|\|\|\|\|\| \| \| \| \| \| \| \| \| \| \| \|\|\|\| \|\| \| \|\| \| ^***** \| \| \|`
`alphabetamotif`	`.. \|\|\|\|\|\| \| \| \| \| \| \| \| \| \| \| \|\|*** \| \|\| *** \| \| \| \|`
`asxturn`	`.. \|\|\|\|\|\| \| \| \| \| \| \| \| \| \| \| \|\|\|\| \| \| \|*** \|\| \| \| \| \|`
`betaturn`	`.. ***\| \| \| \| \| \| \| \| **** \| \| \| ** \|`
`nest`	`.. \|\|\| \|\| \| \| \| * \| \| \| * \| \|\| \| \|\| \| ***`
`niche`	`.. \|**\| \| \| \| \| \| ***** \|\| \|`
`stmotif`	`.. ******** \| \| \| \| *** \|`
`ststaple`	`.. \| \| *** * ***`
`stturn`	`.. ***`

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