triangle PDBeMotif: 2grq  
  coner Sequences coner   coner 3D motifs coner   coner Ligand environment coner   coner Ligand bonds coner
   
coner
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Enzyme   6.3.2.19
Classification ligase    | release date: Mon, Apr 24, 2006
Title crystal structure of human rangap1-ubc9-d127a
Authors A.A.YUNUS, C.D.LIMA
Method X-RAY DIFFRACTION (resolution: 1.70Å)
PDBe Citation   
Ligand bond colours:   *  covalent   *  ionic   *  hydrogen   *  electrostatic   *  van-der-waals   *  plane-atom   *  plane-plane   *  undefined  - Click here to show 5Å bonds
Chain A sequence:
GSHMSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKF
EPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQAPAQAEAYTIYCQNRVEYEKRVRAQAKKFAP
S
Chain B sequence:
STGEPAPVLSSPPPADVSTFLAFPSPEKLLRLGPKSSVLIAQQTDTSDPEKVVSAFLKVSSVFKDEATVRMAVQDAVDAL
MQKAFNSSSFNSNTFLTRLLVHMGLLKSEDKVKAIANLYGPLMALNHMVQQDYFPKALAPLLLAFVTKPNSALESCSFAR
HSLLQTLYKV
Residue colours:  hydrophilic   hydrophobic   intermediate 
Assembly 1     View the assembly/model: ( JMolViewer Download PDB file RasMol script viewer AstexViewer™@MSD-EBI )
Motif search   chain:    Sequence numbers: 
   Using:   φ/ψ    residues code    secondary structures   
 coordinates of:  Cαs Side-chain
 
      View the fragment: rasmol script JMol viewer
chain A : UBIQUITIN-CONJUGATING ENZYME E2 I
member of: CATH:search3.10.110.10GENE3D:searchG3DSA_3.10.110.10PANTHER:searchPTHR24067/searchPTHR24067_SF51PFAM:searchPF00179PROSITE PATTERNS:searchPS00183, PROSITE PROFILES:searchPS50127, SMART:searchSM00212SUPERFAMILY:searchSSF54495UniProt:searchP63279
sec str:  ...hhhhhhhhhhhhhhhhhh.....eeeeee.....eeeeeeeeeee..........eeeeeee..........eeee................hhhhh.........hhhhhhhhhhhhhhh.......hhhhhhhhhhhhhhhhhhhhhhhhhh..
sequence :  ..MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQAPAQAEAYTIYCQNRVEYEKRVRAQAKKFAP
seq num:  ..1         11        21        31        41        51        61        71        81        91        101       111       121       131       141       151    
search RasMol script viewer Motif-ligand binding stats  CAMP_PHOSPHO_SITE ..  |                 |  |      | ||| |  |     | **^* ||||        |  |  |          ||  || ||| ||| ||  | ||  || | |           | |                          |  | 
search RasMol script viewer Motif-ligand binding stats  PKC_PHOSPHO_SITE ..  |                 |  |      | ||| |  |     | || | ||||        |  |  |          ||  || ||| ||| ||  | ||  |^** |           | |                          |  | 
search RasMol script viewer Motif-ligand binding stats  CK2_PHOSPHO_SITE ..  |                 |  |      | ||| |  |     | || ^***||        |  |  |          ||  || ||| ||^***  | ||  ||   |           | |                          |  | 
search RasMol script viewer Motif-ligand binding stats  MYRISTYL ..***                 |  |      | ||| |  |     | || | ||||        |  |  |          ||  || ||| ||| ||  | ||  ||   |           | |                          |  | 
search RasMol script viewer Motif-ligand binding stats  AMIDATION ..                    |  |      | ||| |  |     ^*** | ||||        |  |  |          ||  || ||| ||| ||  | ||  ||   |           | |                          |  | 
search RasMol script viewer Motif-ligand binding stats  UBIQUITIN_CONJUGAT_1 ..                    |  |      | ||| |  |       |  | ||||        |  |  |          ***********^****|  | ||  ||   |           | |                          |  | 
search RasMol script viewer Motif-ligand binding stats  asxturn ..                    |  |      | ||| |  |       |  | ||||        |  |  |           |  || |||  || ||  | ||  ||   |           ***                          |  | 
search RasMol script viewer Motif-ligand binding stats  betabulgeloop ..                    |  |      ***** |  |       |  | ||||        |  |  |           |  |*****  || ||  | ||  ||   |                                        |  | 
search RasMol script viewer Motif-ligand binding stats  betaturn ..                    ****      ****| |  |       *********        |  |  |           |  |****|  ******** ||  ||   |                                        |  | 
search RasMol script viewer Motif-ligand binding stats  nest ..                    |  |        *** |  |       |  | ||||        |  |  |           |  |  ***   |  |  | ||  ||   |                                        |  | 
search RasMol script viewer Motif-ligand binding stats  niche ..                    ****            ****       *********        *******           ****        ****  *******|   |                                        **** 
search RasMol script viewer Motif-ligand binding stats  stmotif ..                                                  *****                                                    *****                                             
search RasMol script viewer Motif-ligand binding stats  stturn ..                                                  ***                                                                                                        

chain B : RAN GTPASE-ACTIVATING PROTEIN 1
member of: CATH:search1.25.40.200GENE3D:searchG3DSA_1.25.40.200PANTHER:searchPTHR24113/searchPTHR24113_SF5PFAM:searchPF07834SUPERFAMILY:searchSSF69099UniProt:searchP46060
sec str:  ....hhhhhhhh.hhhhhhhh..hhhhhhhhh....hhhhhhhhhhhhhh....hhhhhhhhhhhhhhhhhhhhh....hhhhhhhhhhhhh..............hhhhhhhhhhhh.....hhhhhhhhhhhhhh.hhhhhhhhhhhhhhhhhhhh.
sequence :  ..PADVSTFLAFPSPEKLLRLGPKSSVLIAQQTDTSDPEKVVSAFLKVSSVFKDEATVRMAVQDAVDALMQKAFNSSSFNSNTFLTRLLVHMGLLKSEDKVKAIANLYGPLMALNHMVQQDYFPKALAPLLLAFVTKPNSALESCSFARHSLLQTLYKV
seq num:  ..431       441       451       461       471       481       491       501       511       521       531       541       551       561       571       581    
search RasMol script viewer Motif-ligand binding stats  ASN_GLYCOSYLATION ..  | | |                    |  || || |     |   |  || | | |             | ^***|| |      || |||| |||      | |        |  |  | |  |   | | || ||  |           |  | 
search RasMol script viewer Motif-ligand binding stats  PKC_PHOSPHO_SITE ..  | | |                    |  || || |     |   |  || | ^**             |  |  || |      || |||| |||      | |        |  |  | |  |   | | || ||  |           |  | 
search RasMol script viewer Motif-ligand binding stats  CK2_PHOSPHO_SITE ..  | | |                    |  || ^***     |   |  || |                 |  |  || |      || |||| |||      | |        |  |  | |  |   | | || |^***           |  | 
search RasMol script viewer Motif-ligand binding stats  MYRISTYL ..  | | |                    |  ||  | |     |   |  || |                 |  |  || |      || |^*****|      | |        |  |  | |  |   | | || |   |           |  | 
search RasMol script viewer Motif-ligand binding stats  asxmotif ..  *****                    |  ||  | |     |   |  || |                 |  |  || |      || |||| | |      | |        |  |  | |  |   | | || *****           |  | 
search RasMol script viewer Motif-ligand binding stats  asxturn ..  ***                      |  ||  ***     |   |  || |                 |  |  |***      || |||| | |      ***        |  |  | |  |   | | ||                 |  | 
search RasMol script viewer Motif-ligand binding stats  betaturn ..                           |  ||  |       |   |  || |                 |  ****         |****|| | |                 |  |  | ****   | | ||                 **** 
search RasMol script viewer Motif-ligand binding stats  gammaturn ..                           |  ||  |       |   |  |***                 |  |  |         |  |||| | |                 |  |  |        | | ||                      
search RasMol script viewer Motif-ligand binding stats  nest ..                           |  ||  |       |   |  |                    |  |  |         |  **** | |                 |  |  |        | | ||                      
search RasMol script viewer Motif-ligand binding stats  niche ..                           ********       |   ****                    *******         |    |  ***                 *******        | ****                      
search RasMol script viewer Motif-ligand binding stats  schellmannloop ..                                          |   |                                       ******                                     |   |                       
search RasMol script viewer Motif-ligand binding stats  ststaple ..                                          *****                                                                                  *****                       

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