the embryonic anlage of the external genitalia, which emerges as paired swellings ventral to the cloacal membrane, is proposed to be derived from all three germ layers, and gives rise to the penis, clitoris, scrotum, labia, and foreskin [ http://www.informatics.jax.org/accession/anna https://github.com/obophenotype/uberon/issues/1230 ]

Synonyms: undifferentiated genital tubercle

This is just here as a test because I lose it

Term information

Subsets

pheno_slim

depicted by

http://upload.wikimedia.org/wikipedia/commons/d/d6/Gray1119.png

external definition

The eminence in the embryo which develops into the clitoris or penis. [TFD][VHOG]

embryonic anlage of the external genitalia, which emerges as paired swellings ventral to the cloacal membrane, is proposed to be derived from all three germ layers, and gives rise to the penis, clitoris, scrotum, labia, and foreskin; GT development is indistinguishable in male and female mouse embryos until ~E16, when the urethral plate begins to be masculinized to form the penile urethra, marking the beginning of an androgen-dependent phase of sexual differentiation[MP]

external ontology notes

we assume the EMAPA class is the undifferentiated form based on TS timings

has related synonym

phallic tubercle

genital tubercle

tuberculum genitale

tuberculum phallicum

homology notes

In mammalian embryos, male and female external genitalia develop from the genital tubercle.[well established][VHOG]

id

UBERON:0005876

taxon notes

GT development is indistinguishable in male and female mouse embryos until approximately E16, when the urethral plate begins to be masculinized to form the penile urethra, marking the beginning of an androgen-dependent phase of sexual differentiation[MP:0011771]

All amniotes studied to date initiate external genital development with the formation of paired genital swellings. In mammals, archosaurs, and turtles, these swellings merge to form a single genital tubercle, the precursor of the penis and clitoris[PMID:24960313]

todo - add taxon constraints