Cranial nerve fiber tract which is comprised of retinal ganglion cell axons running posterior medially towards the optic chiasm, at which some of the axons cross the midline and after which the structure is termed the optic tract. Transmits visual information from the retina to the brain[ZFA]. [ ]

Synonyms: optic II second cranial nerve 02 optic nerve optic nerve [II] nervus opticus nervus opticus [II] cranial II optic II nerve

This is just here as a test because I lose it

Term information

database cross reference

uberon_slim, efo_slim, pheno_slim, vertebrate_core

latin term
nervus opticus [II] [ FMA:TA FMA:50863 ]

latin term
nervus opticus

taxonomic disambiguation
optic nerve [ FMA:50863 ZFA:0000435 ]

2n [ BIRNLEX:1640 NIFSTD:NeuroNames_abbrevSource ]

editor note

Do not classify under 'cranial nerve', as this is not a true nerve - should be classified as evaginated sensory afferent[ISBN:0471888893]

external definition

A collection of nerve cells that project visual information from the eyes to the brain. (Source: BioGlossary,[TAO]

Fibrous, somatic sensory element covered by a fibrous connective-tissue sheath and is continuous with the layer of nerve cells on the inner surface of the eye.[AAO]

external ontology notes

(relaion to eye): MA, XAO, AAO and BTO consider this part of the eye. This is in contrast to GO, FMA, EHDAA2 (FMA has a class 'intra-ocular part of optic nerve' which represents the region of overlap). Relation to brain: part of diencephalon in EHDAA2, ZFA. In NIF, has the optic nerve root as part, which is a feature part of the diencphalon

has broad synonym


optic nerve

has related synonym


nerve II


homology notes

(...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup (reference 1); The (optic) stalk persists as the optic nerve (reference 2).[well established][VHOG]