The interstitial compartment of the kidney, comprising the extravascular intertubular spaces of the renal parenchyma, with their attendant cellular elements and extracellular substances, bounded on all sides by epithelial and vascular basement membranes. [ ]

Synonyms: renal stroma renal interstitial tissue renal interstitium interstitial tissue of kidney stroma of kidney

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Term information



editor note


function notes

The interstitium is necessarily involved in all intrarenal exchange processes since the reabsorption and secretion of fluid and solutes implicates a transit across the interstitial compartment.

has related synonym

kidney interstitium group



structure notes

The fibroblasts in the interstitium provide the 'skeleton' of the tissue and maintain the three-dimensional architecture of the tissue.