The interstitial compartment of the kidney, comprising the extravascular intertubular spaces of the renal parenchyma, with their attendant cellular elements and extracellular substances, bounded on all sides by epithelial and vascular basement membranes. [ http://orcid.org/0000-0002-6601-2165 http://www.ncbi.nlm.nih.gov/pubmed/18575881 https://doi.org/10.1038/ki.1991.49 ]
Synonyms: renal stroma renal interstitial tissue renal interstitium interstitial tissue of kidney stroma of kidney
Term information
- EMAPA:28518
- null:http://www.snomedbrowser.com/Codes/Details/362210003
- FMA:70983
- MA:0002616
- NCIT:C33459
pheno_slim
The interstitium is necessarily involved in all intrarenal exchange processes since the reabsorption and secretion of fluid and solutes implicates a transit across the interstitial compartment.
The fibroblasts in the interstitium provide the 'skeleton' of the tissue and maintain the three-dimensional architecture of the tissue.