The transient outer neural tube region that contains the first generated post-mitotic neurons that receive synaptic input from thalamic axons and in turn project axons to the developing cortical plate. [ http://en.wikipedia.org/wiki/Subplate MP : 0008440 https://github.com/obophenotype/mouse-anatomy-ontology/issues/1 ]

This is just here as a test because I lose it

Term information

Subsets

pheno_slim

abbreviation
SP [ BRAINSPAN : BRAINSPAN ]
definition
  • The transient outer neural tube region that contains the first generated post-mitotic neurons that receive synaptic input from thalamic axons and in turn project axons to the developing cortical plate.
development notes
  • The transient fetal subplate zone, together with the marginal zone and the cortical plate, represents the developmental anlage of the mammalian cerebral cortex. It serves as a waiting compartment for growing cortical afferents; its cells are involved in the establishment of pioneering cortical efferent projections and transient fetal circuitry, and apparently have a number of other developmental roles. The subplate zone is a phylogenetically recent structure and it is most developed in the human brain. Subplate neurons are among the first generated neurons in the mammalian cerebral cortex [1]. These neurons disappear during postnatal development and are important in establishing the correct wiring [2][3] and functional maturation [4] of the cerebral cortex. Subplate neurons appear to be selectively sensitive to injury (such as hypoxia) which in humans are associated with motor and cognitive defects
has exact synonym
  • subplate zone
  • cerebral cortex subplate
  • subplate
id
  • UBERON:0004035