Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]. [ http://en.wikipedia.org/wiki/Sclerotome https://github.com/obophenotype/uberon/issues/316 XB : curator ]

This is just here as a test because I lose it

Term information

database cross reference
Subsets

uberon_slim, pheno_slim, vertebrate_core

plural term
sclerotomes [ TAO : 0001080 ]
definition
  • Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP].
depicted by
  • http://upload.wikimedia.org/wikipedia/commons/9/96/Gray65.png
external definition
  • Skeletogenic portion of somites.[AAO]
external ontology notes
  • part_of somite in XAO
has exact synonym
  • sclerotomes
has related synonym
  • sclerotomus
homology notes
  • The vertebrate sclerotome has no equivalent in amphioxus and is a novelty linked with the evolution of the axial skeleton.[well established][VHOG]
id
  • UBERON:0003089