The specialized glial structure (non-neuronal cells) situated at the ventral midline of the embryonic neural tube; this structure spans the anteroposterior axis from the midbrain to the tail regions, separating the left and right basal plates of the developing neural tube, and serves as an organizer to ventralize tissues in the embryo as well as to guide neuronal positioning and differentiation along the dorsoventral axis of the neural tube. [ http://www.informatics.jax.org/accession/anna http://en.wikipedia.org/wiki/Floor_plate http://www.ncbi.nlm.nih.gov/pubmed/15738958 http://amigo.geneontology.org/amigo/term/GO:0021508 ]
Term information
- EMAPA:32684
- ZFA:0000022
- EFO:0003473
- AAO:0011041
- RETIRED_EHDAA2:0000545
- TAO:0000022
- BTO:0001720
- null:http://en.wikipedia.org/wiki/Floor_plate
uberon_slim, efo_slim, pheno_slim, vertebrate_core
- The specialized glial structure (non-neuronal cells) situated at the ventral midline of the embryonic neural tube; this structure spans the anteroposterior axis from the midbrain to the tail regions, separating the left and right basal plates of the developing neural tube, and serves as an organizer to ventralize tissues in the embryo as well as to guide neuronal positioning and differentiation along the dorsoventral axis of the neural tube.
- http://upload.wikimedia.org/wikipedia/commons/8/89/Gray642.png
- Organizing center consisting of a small group of cells located at the ventral midline of the neural tube that influences the development of the nervous system, governing the specification of neuronal cell types and directing axonal trajectories.[AAO]
- although this is classically defined as being located on the neural tube, in many AOs the floor plate continues post-embryonically after the neural tube has ceased to exist. Consider 'floor plate of neural tube'.
- floorplate
- uberon
- FP
- bodenplatte
- ventral plate
- UBERON:0003079
Term relations
- embryonic tissue
- ectoderm-derived structure
- cell layer
- mesoderm-derived structure
- in ventral side of some neural tube
- immediate transformation of some presumptive floor plate
- composed primarily of some glial cell
- develops from some notochord
- develops from some presumptive floor plate
- produces some spondin-1
- part of some neural tube