floor plate

The specialized glial structure (non-neuronal cells) situated at the ventral midline of the embryonic neural tube; this structure spans the anteroposterior axis from the midbrain to the tail regions, separating the left and right basal plates of the developing neural tube, and serves as an organizer to ventralize tissues in the embryo as well as to guide neuronal positioning and differentiation along the dorsoventral axis of the neural tube. [ http://www.informatics.jax.org/accession/anna http://en.wikipedia.org/wiki/Floor_plate http://www.ncbi.nlm.nih.gov/pubmed/15738958 http://amigo.geneontology.org/amigo/term/GO:0021508 ]

Preferred root terms

All terms

This is just here as a test because I lose it

database cross reference

Subsets

uberon_slim, efo_slim, pheno_slim, vertebrate_core

definition

The specialized glial structure (non-neuronal cells) situated at the ventral midline of the embryonic neural tube; this structure spans the anteroposterior axis from the midbrain to the tail regions, separating the left and right basal plates of the developing neural tube, and serves as an organizer to ventralize tissues in the embryo as well as to guide neuronal positioning and differentiation along the dorsoventral axis of the neural tube.

depicted by

external definition

Organizing center consisting of a small group of cells located at the ventral midline of the neural tube that influences the development of the nervous system, governing the specification of neuronal cell types and directing axonal trajectories.[AAO]

external ontology notes

although this is classically defined as being located on the neural tube, in many AOs the floor plate continues post-embryonically after the neural tube has ceased to exist. Consider 'floor plate of neural tube'.

has exact synonym

has obo namespace

has related synonym

Subclass of:

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has potential to develop into

part of