Region at the periphery of the retina where retinal stem cells are located. After 60 hpf, the CMZ is the source of most retinal growth.[Wehman et al, 2005] [ http://zfin.org/curator ]

Synonyms: peripheral growth zone retinal ciliary marginal zone

This is just here as a test because I lose it

Term information

database cross reference
  • VHOG:0000088
  • EFO:0003668
  • ZFA:0001289
  • XAO:0000086
  • AAO:0010342
  • TAO:0001289
Subsets

uberon_slim, efo_slim

external definition

Region at the periphery of the retina where retinal stem cells are located. After 60 hpf, the CMZ is the source of most retinal growth. Wehman et al, 2005.[TAO]

has related synonym

CMZ

retinal proliferative zone

circumferential germinal zone

homology notes

The retina of all vertebrates develops via similar mechanisms. Toward the end of retinal histogenesis, proliferating progenitors and newly generated cells are confined to peripheral regions of the retina. In fish and amphibians, this region is maintained after embryonic development and becomes the CMZ (ciliary margin zone). A CMZ exists in birds but compared to that of fish and amphibians this region produces much less new retina as the globe of the eye expands postnatally. At least some of the molecular mechanisms that regulate the addition of new cells in this zone appear to have been conserved from fish to birds.[well established][VHOG]

id

UBERON:0003065

Term relations