The part of the heart connecting the atrium to the cardiac ventricle[ZFA]. In the developing heart, the constriction between the atrium and ventricle constitutes the atrial canal, and indicates the site of the future atrioventricular valves[WP]. [ https://github.com/obophenotype/uberon/issues/38 http://en.wikipedia.org/wiki/Atrioventricular_canal ]

Synonyms: AV canal atrio-ventricular canal atrial canal AVC

This is just here as a test because I lose it

Term information

Subsets

uberon_slim, pheno_slim, vertebrate_core

abbreviation
AVC [ ZFA:0001315 ]

contributor

https://github.com/cmungall

https://github.com/mellybelly

https://github.com/rfoulger

depicted by

http://upload.wikimedia.org/wikipedia/commons/d/d8/Gray464.png

development notes

The right side of the AVC becomes the tricuspid valve whereas the left side of the AVC will become the bicuspid valve

external definition

The canal connecting the primitive atrium and ventricle in fishes and amniotes embryo. [TFD][VHOG]

external ontology notes

this is a lumen in EHDAA2

function notes

In the embryo, the atrioventricular canal delays the impulse from atrium to ventricle[PMID:22984480]

has related synonym

canalis atrioventricularis

ependymal canal

homology notes

The heart is the first organ to form and function in a vertebrate. (...) Septation of the AV canal is initiated with the formation of inferior and superior endocardial cushions in response to signaling from the overlying myocardium. (...) Analysis of zebrafish mutants with cardiovascular defects uncovered a previously unexpected level of conservation between zebrafish and human cardiovascular physiology.[uncertain][VHOG]

id

UBERON:0002087