A spherical aggregation of cells in the ovary that contains a single oocyte[WP,modified]. [ http://www.repropedia.org/ovarian-follicle http://en.wikipedia.org/wiki/Ovarian_follicle ]

This is just here as a test because I lose it

Term information

Subsets

uberon_slim, pheno_slim, vertebrate_core, human_reference_atlas

definition
  • A spherical aggregation of cells in the ovary that contains a single oocyte[WP,modified].
depicted by
  • http://upload.wikimedia.org/wikipedia/commons/c/ca/Human_ovarian_follicle.jpg
  • https://upload.wikimedia.org/wikipedia/commons/e/e6/Primary_follicle-4.JPG
editor note
  • TODO - align subtypes based on staging, which is taxon-specific
external definition
  • Oocyte development of zebrafish has been divided into five stages based on morphological criteria and on physiological and biochemical events. Stage I follicles (less than 140 microns) are primary growth stage, stage II follicles (140-340 microns) are cortical alveolus stage, stage III (340-690 microns) are vitellogenesis, stage IV (690-730 microns) are oocyte maturation, and stage V follicles are matured egg. Selman et al, 1993.[TAO]
function notes
  • The somatic cell component of the follicle produces hormones important for oocyte development and proper endocrine function
has exact synonym
  • ovary follicle
  • follicle of ovary viewed macroscopically
  • follicle of ovary
has related synonym
  • folliculi ovarici primarii
  • egg follicle
  • folliculi ovarici vesiculosi
homology notes
  • Examination of different vertebrate species shows that the adult gonad is remarkably similar in its morphology across different phylogenetic classes. Surprisingly, however, the cellular and molecular programs employed to create similar organs are not evolutionarily conserved.[uncertain][VHOG]
id
  • UBERON:0001305
present in taxon
  • http://purl.obolibrary.org/obo/NCBITaxon_9606
taxon notes
  • These structures are periodically initiated to grow and develop, culminating in ovulation of usually a single competent oocyte in humans. These eggs/ova are only developed once every menstrual cycle (e.g. once a month in humans)