JSON

heart

^ http://purl.obolibrary.org/obo/UBERON_0000948


A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ. [ http://en.wikipedia.org/wiki/Heart http://orcid.org/0000-0002-6601-2165 ]

Synonyms: vertebrate heart, chambered heart

Term info

database cross reference
Subsets

uberon_slim, efo_slim, pheno_slim, vertebrate_core, organ_slim, major_organ

taxonomic disambiguation
branchial heart

axiom lost from external ontology

relationship type change: differentiates_from lateral plate mesoderm (AAO:0010574) CHANGED TO: develops_from lateral plate mesoderm (UBERON:0003081)[AAO]

comment

Taxon notes:" the ascidian tube-like heart lacks chambers....The ascidian heart is formed after metamorphosis as a simple tube-like structure with a single-layered myoepithelium that is continuous with a single-layered pericar- dial wall. It lacks chambers and endocardium.... The innovation of the chambered heart was a key event in vertebrate evolution, because the chambered heart generates one-way blood flow with high pressure, a critical requirement for the efficient blood supply of large-body vertebrates... all extant vertebrates have hearts with two or more chambers (Moorman and Christoffels 2003)" https://doi.org/10.1101/gad.1485706

external definition

Blood pumping organ composed of four chambers: sinus venosus, atrium, cardiac ventricle and bulbus arteriosus.[TAO], Part of the circulatory system responsible for pumping blood; composed of three chambers--two atria and one ventricle.[AAO]

has narrow synonym

branchial heart

has related synonym

Herz@de, cardium

homology notes

As noted, the hearts of birds and mammals have four chambers that arises from the two chambers (atrium and ventricle) of the fish heart.[well established][VHOG]

id

UBERON:0000948