A dengue virus genome polyprotein proteolytic cleavage product that is derived from dengue virus genome polyprotein, N-glycosylated form and that contains the entire non-structural region of the dengue virus genome polyprotein only and is responsible for directing viral genomic RNA replication, including synthesizing negative- and positive-strand RNAs and forming the viral RNA cap structure. It consists of NS1, NS2A, NS3, NS4A, 2K, NS4B, and NS5. [ http://www.ncbi.nlm.nih.gov/pubmed/22022449 http://www.ncbi.nlm.nih.gov/pubmed/1433530 PRO:ES ]

Synonyms: Non-structural proteins DenV-NS12345 NS1-NS2A-NS2B-NS3-NS4A-NS4B-NS5 Nonstructural proteins