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inhibitory smad protein

^ http://purl.obolibrary.org/obo/PR_000000099


A smad protein that is an antagonist of the transforming growth factor beta (TGF-beta) superfamily signaling pathways. It lacks the C-terminal SSxS motif, necessary for receptor mediated phosphorylation that is present in the receptor-regulated smads. [ http://www.ncbi.nlm.nih.gov/pubmed/11532220 ]

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