ACTH-dependent Cushing syndrome
Adrenocorticotropic hormone dependent Cushing syndrome (ACTH-dependent CS) is a form of endogenous CS (see this term) caused by abnormal production of ACTH due, in 80% of cases, to ACTH oversecretion by a pituitary adenoma (Cushing disease, CD) and in 20% of cases to ectopic ACTH secretion (CS due to EAS; see these terms) by an extrapituitary tumor (in 50% of cases originating in the lungs or less commonly in the thymus, pancreas, adrenal gland or thyroid) or very rarely due to a tumor secreting both ACTH and corticotrophin-releasing hormone (CRH).
Synonyms: Corticotropin-dependent Cushing syndrome, Adrenocorticotropic hormone-dependent Cushing syndrome, ACTH-dependent CS
- Rare male infertility due to adrenal disorder
- Rare female infertility due to an adrenal disorder
- Cushing syndrome
- present_in some Worldwide and has_point_prevalence_range some Unknown_epidemiological_range
- has_annual_incidence_range some 1-9 / 1 000 000 and present_in some Worldwide and has_annual_incidence_average_value value 0.55