ACTH-dependent Cushing syndrome

^ http://www.orpha.net/ORDO/Orphanet_99892

Adrenocorticotropic hormone dependent Cushing syndrome (ACTH-dependent CS) is a form of endogenous CS (see this term) caused by abnormal production of ACTH due, in 80% of cases, to ACTH oversecretion by a pituitary adenoma (Cushing disease, CD) and in 20% of cases to ectopic ACTH secretion (CS due to EAS; see these terms) by an extrapituitary tumor (in 50% of cases originating in the lungs or less commonly in the thymus, pancreas, adrenal gland or thyroid) or very rarely due to a tumor secreting both ACTH and corticotrophin-releasing hormone (CRH).

Synonyms: Corticotropin-dependent Cushing syndrome, Adrenocorticotropic hormone-dependent Cushing syndrome, ACTH-dependent CS

Term info

database cross reference
  • UMLS:C0342442 (E (exact mapping (the terms and the concepts are equivalent)))
  • ICD-10:E24.0 (NTBT (narrower term maps to a broader term))

UMLS:C0342442, ICD-10:E24.0