Precursor T-cell acute lymphoblastic leukemia

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A rare acute lymphoblastic leukemia characterized by a neoplasm of lymphoblasts committed to the T-cell lineage, involving bone marrow and blood. A value of >25% bone marrow blasts may be used to define leukemia (as opposed to lymphoma) in cases with the presence of a mass lesion in addition to bone marrow involvement. Patients typically present with leukocytosis, and frequently with a large mediastinal or other tissue mass. Lymphadenopathy and hepatosplenomegaly are common.

Synonyms: Precursor T-cell acute lymphocytic leukemia/lymphoma Precursor T-cell acute lymphocytic leukemia T-ALL Precursor T-cell acute lymphoblastic leukemia/lymphoma

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