Precursor B-cell acute lymphoblastic leukemia

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A rare acute lymphoblastic leukemia characterized by infiltration of bone marrow and peripheral blood by small to medium-sized blast cells typically positive for the B-cell markers CD19, cCD79a, and cCD22. Predilection sites for extramedullary involvement are the central nervous system, lymph nodes, spleen, liver, and testes. Patients present with evidence of bone marrow failure (i. e. thrombocytopenia, anemia, and/or neutropenia) and variable leukocyte count, as well as lymphadenopathy, hepatomegaly, splenomegaly, bone pain, and arthralgias.

Synonyms: B-ALL Precursor B-cell acute lymphocytic leukemia Precursor B-cell acute lymphocytic leukemia/lymphoma Precursor B-cell acute lymphoblastic leukemia/lymphoma

This is just here as a test because I lose it

Term information

database cross reference
hasDbXref

ICD-10:C91.0

OMIM:615545

ICD-10:C83.5

UMLS:C1292769

UMLS:C0006413

notation

ORPHA:99860