Acute myeloblastic leukemia with maturation

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A rare, acute myeloid leukemia characterized by evidence of granulocytic maturation and more than 20% of blast cells in the bone marrow and/or peripheral blood. The maturing non-blast granulocytic cells account for greater than or equal to 10% and monocytic cells less than or equal to 20% of the bone marrow cells. Various degrees of anemia, thrombocytopenia, or pancytopenia are present. Frequent clinical manifestations include fatigue, fever, bleeding disorders, and organomegaly, especially hepatosplenomegaly.

Synonyms: Acute myeloblastic leukemia M2 AML M2

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Term information

database cross reference
  • UMLS:C1879321 (E (Exact mapping: the two concepts are equivalent))
  • ICD-10:C92.0 (NTBT (ORPHA code's Narrower Term maps to a Broader Term))