Acute myeloid leukemia with minimal differentiation

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A rare subtype of acute myeloid leukemia characterized by clonal proliferation of poorly differentiated myeloid blasts in the bone marrow, blood or other tissues. It usually presents with anemia, thrombocytopenia and other nonspecific symptoms related to ineffective hematopoesis (fatigue, bleeding and bruising, recurrent infections, bone pain) and/or extramedullary site involvement (gingivitis, splenomegaly). Low remission rates are reported.

Synonyms: AML M0 Minimally differentiated acute myeloblastic leukemia

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Term information

database cross reference
  • UMLS:C0522631 (E (Exact mapping: the two concepts are equivalent))
  • ICD-10:C92.0 (NTBT (ORPHA code's Narrower Term maps to a Broader Term))