Acute myeloid leukemia and myelodysplastic syndromes related to radiation

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A subgroup of therapy-related myeloid neoplasms (t-MN), associated with treatment of an unrelated neoplastic disease with radiation. The neoplastic cells typically harbor unbalanced aberrations of chromosomes 5 and 7 (monosomy 5/del(5q) and monosomy 7/del(7q)) or a complex karyotype. Patients frequently present with multilineage dysplasia and cytopenias 5-10 years after exposure.

Synonyms: AML and myelodysplastic syndromes related to radiation

This is just here as a test because I lose it

Term information

database cross reference
  • ICD-10:D46 (ND (not yet decided/unable to decide))
hasDbXref

ICD-10:D46

notation

ORPHA:164726