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Interleukin-6

^ http://purl.obolibrary.org/obo/NCIT_C20451


Interleukin-6 (212 aa, ~24 kDa) is encoded by the human IL6 gene. This protein is involved in signaling affecting a wide variety of cell types including monocytes, lymphocytes, hepatocytes and nerve cells. [ NCI ]

Synonyms: B-Cell Stimulatory Factor-2, CDF, HPGF, Hybridoma Growth Factor, interleukin-6, Interleukin-6, Interleukin 6, IFN-Beta-2, IL6 Protein, Myeloid Differentiation Inducing Protein, B-Cell Differentiation Factor, Interferon, Beta-2, HSF, B Cell Differentiation Factor 2, BSF2, IFNB2, HGF, CTL Differentiation Factor, Interferon Beta-2, Plasmacytoma Growth Factor, Interleukin BSF-2, IL-6, Hepatocyte Stimulating Factor, B-Cell Stimulatory Factor 2, BSF-2, IL6, Sigosix, Hepatocyte Stimulatory Factor, IFN Beta 2

Term info

Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

ALT DEFINITION

One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. Interleukin-6 is made mainly by some T lymphocytes. It causes B lymphocytes to make more antibodies and also causes fever by affecting areas of the brain that control body temperature. Interleukin-6 made in the laboratory is used as a biological response modifier to boost the immune system in cancer therapy. Interleukin-6 is a type of cytokine. Also called IL-6.

Display Name

Interleukin-6

Legacy Concept Name

Interleukin-6

OMIM Number

147620

Preferred Name

Interleukin-6

Semantic Type

Amino Acid, Peptide, or Protein, Immunologic Factor

Swiss Prot

P05231

UMLS CUI

C1698754

code

C20451

Term relations

Equivalent to:

Subclass of: