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Adoptive Immunotherapy

^ http://purl.obolibrary.org/obo/NCIT_C15351


A technique for enhancing cell-mediated immunity by: 1) artificially increasing the number of specific immunocompetent cells through inoculation of either ex-vivo expanded primarily activated cytotoxic lymphocytes or genetically engineered lymphocytes with enhanced cytotoxic ability or 2) by altering tumor cells to make them more immunogenic. [ NCI ]

Synonyms: Adoptive Cell Transfer, Adoptive Cell Immunotherapy, ACT, adoptive cellular immunotherapy, Adoptive Cell Transfer Immunotherapy, adoptive cellular therapy, Adoptive Cell Transfer Therapy, Adoptive Immunotherapy, ACT Therapy, cellular adoptive immunotherapy

Term info

Subsets

NCIT_C116977, NCIT_C118169

ALT DEFINITION

A treatment used to help the immune system fight diseases, such as cancer and infections with certain viruses. T cells are collected from a patient and grown in the laboratory. This increases the number of T cells that are able to kill cancer cells or fight infections. These T cells are given back to the patient to help the immune system fight disease.

DesignNote

The concept does not refer to anticancer vaccines and immune modulation through the therapeutic use of cytokines, cell receptors, or other substances.

Display Name

Adoptive Immunotherapy

Legacy Concept Name

Adoptive_Immunotherapy

Preferred Name

Adoptive Immunotherapy

Semantic Type

Therapeutic or Preventive Procedure

UMLS CUI

C0079613

code

C15351

Term relations