Ewing sarcoma/peripheral primitive neuroectodermal tumor of bone

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A spectrum of malignant tumors arising from the bone and characterized morphologically by the presence of small round cells. Ewing sarcoma and peripheral primitive neuroectodermal tumor represent the ends of a spectrum, with Ewing sarcoma lacking evidence of neural differentiation and the markers that characterize the peripheral primitive neuroectodermal tumor. Ewing sarcoma and peripheral primitive neuroectodermal tumor may share cytogenetic abnormalities, proto-oncogene expression, cell culture and immunohistochemical abnormalities. Pain and the presence of a mass are the most common clinical symptoms. [ NCIT:C35871 ]

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Term information

database cross reference
  • NCIT:C35871 (MONDO:equivalentTo)
  • UMLS:C1333481 (NCIT:C35871)
definition

A spectrum of malignant tumors arising from the bone and characterized morphologically by the presence of small round cells. Ewing sarcoma and peripheral primitive neuroectodermal tumor represent the ends of a spectrum, with Ewing sarcoma lacking evidence of neural differentiation and the markers that characterize the peripheral primitive neuroectodermal tumor. Ewing sarcoma and peripheral primitive neuroectodermal tumor may share cytogenetic abnormalities, proto-oncogene expression, cell culture and immunohistochemical abnormalities. Pain and the presence of a mass are the most common clinical symptoms.

exactMatch

http://purl.obolibrary.org/obo/NCIT_C35871

http://linkedlifedata.com/resource/umls/id/C1333481

has exact synonym

Ewing sarcoma/peripheral primitive neuroectodermal tumor of bone

bone tissue Ewing sarcoma/peripheral primitive neuroectodermal tumor

Ewing's sarcoma/peripheral primitive neuroectodermal tumor of bone

id

MONDO:0021123