IgG4-related dacryoadenitis and sialadenitis

Go to external page http://purl.obolibrary.org/obo/MONDO_0019191


IgG4-related dacryoadenitis and sialoadenitis (Mikulicz disease) is an IgG4-related sclerosing disease characterized by persistent, usually painless, bilateral enlargement of the lacrimal, parotid, and submandibular glands associated with elevated levels of serum immunoglobulin (Ig) G4 and with lymphocyte and IgG4-positive plasmacyte infiltration. It predominantly causes mouth and eye dryness but can also affect other organs such as the lungs, liver, and kidneys, and be accompanied by complications such as autoimmune pancreatitis (AIP), retroperitoneal fibrosis, and tubulointerstitial nephritis. [ Orphanet:79078 ]

This is just here as a test because I lose it

Term information

database cross reference
  • MESH:D008882 (Orphanet:79078)
  • NCIT:C34819 (NCIT:C34819)
  • SCTID:7826003 (MONDO:equivalentTo)
  • DOID:12900 (MONDO:equivalentTo)
  • MedDRA:10052317 (Orphanet:79078)
  • MedDRA:10051457 (Orphanet:79078)
  • GARD:0007043 (MONDO:equivalentTo)
  • ICD10:K11.8 (Orphanet:79078)
  • Orphanet:79078 (MONDO:equivalentTo)
  • UMLS:C0026103 (Orphanet:79078)
Subsets

gard_rare, ordo_disease

closeMatch

http://identifiers.org/snomedct/196478007

definition

IgG4-related dacryoadenitis and sialoadenitis (Mikulicz disease) is an IgG4-related sclerosing disease characterized by persistent, usually painless, bilateral enlargement of the lacrimal, parotid, and submandibular glands associated with elevated levels of serum immunoglobulin (Ig) G4 and with lymphocyte and IgG4-positive plasmacyte infiltration. It predominantly causes mouth and eye dryness but can also affect other organs such as the lungs, liver, and kidneys, and be accompanied by complications such as autoimmune pancreatitis (AIP), retroperitoneal fibrosis, and tubulointerstitial nephritis.

exactMatch

http://identifiers.org/mesh/D008882

http://identifiers.org/snomedct/7826003

http://purl.obolibrary.org/obo/DOID_12900

http://www.orpha.net/ORDO/Orphanet_79078

http://identifiers.org/meddra/10052317

http://purl.obolibrary.org/obo/NCIT_C34819

http://identifiers.org/meddra/10051457

http://linkedlifedata.com/resource/umls/id/C0026103

has exact synonym

chronic dacryoadenitis and sialadenitis

Mikulicz's disease

Mikulicz disease

has related synonym

Mikulicz syndrome (former)

Mikulicz disease (former)

Mikulicz's disease (former)

id

MONDO:0019191

seeAlso

https://rarediseases.info.nih.gov/diseases/7043/igg4-related-dacryoadenitis-and-sialadenitis