Malignant hyperthermia (MH) is a pharmacogenetic disorder of skeletal muscle that presents as a hypermetabolic response to potent volatile anesthetic gases such as halothane, sevoflurane, desflurane and the depolarizing muscle relaxant succinylcholine, and rarely, to stresses such as vigorous exercise and heat. [ Orphanet : 423 ]

This is just here as a test because I lose it

Term information

database cross reference
Subsets

ordo_disease, clingen

closeMatch
  • http://identifiers.org/meddra/10020844
definition
  • Malignant hyperthermia (MH) is a pharmacogenetic disorder of skeletal muscle that presents as a hypermetabolic response to potent volatile anesthetic gases such as halothane, sevoflurane, desflurane and the depolarizing muscle relaxant succinylcholine, and rarely, to stresses such as vigorous exercise and heat.
exactMatch
  • http://identifiers.org/mesh/D008305
  • https://omim.org/phenotypicSeries/PS145600
  • http://www.orpha.net/ORDO/Orphanet_423
  • http://purl.obolibrary.org/obo/DOID_8545
  • http://identifiers.org/snomedct/405501007
  • http://purl.obolibrary.org/obo/NCIT_C84869
  • http://linkedlifedata.com/resource/umls/id/C0024591
excluded subClassOf
  • http://purl.obolibrary.org/obo/MONDO_0002254
has exact synonym
  • malignant hyperpyrexia due to anesthesia
  • malignant hyperthermia of anesthesia
  • malignant hyperpyrexia
  • anesthesia related hyperthermia
  • malignant hyperthermia syndrome
  • hyperthermia of anesthesia
  • malignant hyperthermia
id
  • MONDO:0018493
should conform to
  • http://purl.obolibrary.org/obo/mondo/patterns/OMIM_phenotypic_series.yaml