progressive multifocal leukoencephalopathy

Go to external page http://purl.obolibrary.org/obo/MONDO_0016318


Progressive multifocal leukoencephalopathy (PML) is a neurological disorder that damages the myelin that covers and protects nerves in the white matter of the brain. It is caused by the JC virus (JCV). By age 10, most people have been infected with this virus, but itrarelycauses symptoms unless the immune system becomes severely weakened.The disease occurs, rarely, in organ transplant patients; people undergoing chronic corticosteroid or immunosuppressive therapy; and individuals with cancer, such as Hodgkins disease, lymphoma, and sarcoidosis. PML is most common among individuals with acquired immune deficiency syndrome (AIDS). [ https://rarediseases.info.nih.gov/diseases/7468/progressive-multifocal-leukoencephalopathy ]

This is just here as a test because I lose it

Term information

database cross reference
  • SCTID:22255007 (MONDO:equivalentTo)
  • UMLS:C0023524 (Orphanet:217260)
  • ICD9:046.3 (i2s)
  • GARD:0007468 (MONDO:equivalentTo)
  • MedDRA:10036807 (Orphanet:217260)
  • DOID:643 (MONDO:equivalentTo)
  • EFO:0007455 (MONDO:equivalentTo)
  • Orphanet:217260 (MONDO:equivalentTo)
  • MESH:D007968 (Orphanet:217260)
  • ICD10:A81.2 (Orphanet:217260)
  • NCIT:C26815 (MONDO:equivalentTo)
  • COHD:433957 (MONDO:equivalentTo)
Subsets

gard_rare, ordo_disease

abbreviation
PML [ Orphanet:217260 CSP2005:2042-2309 DOID:643 ]

definition

Progressive multifocal leukoencephalopathy (PML) is a neurological disorder that damages the myelin that covers and protects nerves in the white matter of the brain. It is caused by the JC virus (JCV). By age 10, most people have been infected with this virus, but itrarelycauses symptoms unless the immune system becomes severely weakened.The disease occurs, rarely, in organ transplant patients; people undergoing chronic corticosteroid or immunosuppressive therapy; and individuals with cancer, such as Hodgkins disease, lymphoma, and sarcoidosis. PML is most common among individuals with acquired immune deficiency syndrome (AIDS).

exactMatch

http://identifiers.org/mesh/D007968

http://identifiers.org/meddra/10036807

http://identifiers.org/snomedct/22255007

http://linkedlifedata.com/resource/umls/id/C0023524

http://purl.obolibrary.org/obo/NCIT_C26815

http://www.orpha.net/ORDO/Orphanet_217260

http://purl.obolibrary.org/obo/DOID_643

has exact synonym

PML

progressive multifocal leukoencephalitis

has related synonym

leukoencephalopathy, progressive multifocal

id

MONDO:0016318

seeAlso

https://rarediseases.info.nih.gov/diseases/7468/progressive-multifocal-leukoencephalopathy

Term relations