Indomethacin embryofetopathy refers to the manifestations that may be observed in a fetus or newborn when the mother has taken indomethacin, a potent prostaglandin inhibitor and tocolytic agent that can cross placenta, during pregnancy. Reported adverse fetal/neonatal effects include decreased renal function resulting in oligohydramnios, closure of the ductus arteriosus, and delayed cardiovascular adaptation at birth. These effects are usually transient and reversible. Indomethacin may also be a risk factor for cerebral injury (periventricular leukomalacia) and necrotizing enterocolitisin preterm infants. [ Orphanet:1909 ]

This is just here as a test because I lose it

Term information

database cross reference
  • Orphanet:1909 (MONDO:equivalentTo)
  • GARD:0002994 (Orphanet-shared)
  • SCTID:715430001 (MONDO:equivalentTo)
  • ICD10:Q86.8 (Orphanet:1909)
  • UMLS:CN200656 (MONDO:equivalentTo)
  • UMLS:C4275138 (MONDO:equivalentTo)
Subsets

ordo_malformation_syndrome

definition

Indomethacin embryofetopathy refers to the manifestations that may be observed in a fetus or newborn when the mother has taken indomethacin, a potent prostaglandin inhibitor and tocolytic agent that can cross placenta, during pregnancy. Reported adverse fetal/neonatal effects include decreased renal function resulting in oligohydramnios, closure of the ductus arteriosus, and delayed cardiovascular adaptation at birth. These effects are usually transient and reversible. Indomethacin may also be a risk factor for cerebral injury (periventricular leukomalacia) and necrotizing enterocolitisin preterm infants.

exactMatch

http://linkedlifedata.com/resource/umls/id/C4275138

http://linkedlifedata.com/resource/umls/id/CN200656

http://www.orpha.net/ORDO/Orphanet_1909

http://identifiers.org/snomedct/715430001

has exact synonym

fetal indomethacin syndrome

has related synonym

antenatal indomethacin exposure

id

MONDO:0016005