A rare, highly aggressive and lethal carcinoma that affects children and young adults. It arises from midline epithelial structures, most commonly the head, neck, and mediastinum. It is a poorly differentiated carcinoma and is characterized by mutations and rearrangement of the NUT gene. A balanced translocation t(15;19) is present that results in the creation of a fusion gene involving the NUT gene, most commonly BRD4-NUT fusion gene. [ NCIT:C45716 ]

This is just here as a test because I lose it

Term information

database cross reference
  • ICD10:C80.9 (Orphanet:443167)
  • UMLS:CN237663 (MONDO:equivalentTo)
  • Orphanet:443167 (MONDO:equivalentTo)
  • Wikipedia:NUT_midline_carcinoma (EFO:0005783)
  • EFO:0005783 (MONDO:equivalentTo)
  • DOID:0060463 (MONDO:equivalentTo)
  • NCIT:C45716 (exact-label-match)
  • UMLS:C1707291 (NCIT:C45716)
  • ONCOTREE:NMCHN (MONDO:equivalentTo)
Subsets

ordo_disease

abbreviation
NMC [ Orphanet:443167 ]

definition

A rare, highly aggressive and lethal carcinoma that affects children and young adults. It arises from midline epithelial structures, most commonly the head, neck, and mediastinum. It is a poorly differentiated carcinoma and is characterized by mutations and rearrangement of the NUT gene. A balanced translocation t(15;19) is present that results in the creation of a fusion gene involving the NUT gene, most commonly BRD4-NUT fusion gene.

exactMatch

http://linkedlifedata.com/resource/umls/id/C1707291

http://purl.obolibrary.org/obo/NCIT_C45716

http://linkedlifedata.com/resource/umls/id/CN237663

http://www.orpha.net/ORDO/Orphanet_443167

http://purl.obolibrary.org/obo/DOID_0060463

has exact synonym

NMC

carcinoma with t(15;19)(q13;p13.1) translocation

NUT carcinoma

Midline carcinoma of children and Young adults with NUT rearrangement

nuclear protein in testis midline carcinoma

NUT Midline carcinoma

has related synonym

NUT midline carcinoma of the head and neck

id

MONDO:0005563

Term relations