Measurement of the directed movement of particles in a microscopic temperature gradient. Any change of the hydration shell of biomolecules due to changes in their structure/conformation results in a relative change of movement along the temperature gradient and is used to determine binding affinities, binding kinetics and activity kinetics. Events such as the phosphorylation of a protein or the binding of small molecules to a target can be monitored. [ http://www.ncbi.nlm.nih.gov/pubmed/17164337 ]

This is just here as a test because I lose it

Term information

Subsets

PSI-MI_slim

created by

orchard

creation date

2012-08-10T12:20:37Z

definition

Measurement of the directed movement of particles in a microscopic temperature gradient. Any change of the hydration shell of biomolecules due to changes in their structure/conformation results in a relative change of movement along the temperature gradient and is used to determine binding affinities, binding kinetics and activity kinetics. Events such as the phosphorylation of a protein or the binding of small molecules to a target can be monitored.

id

MI:1247

Term relations

Subclass of: