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Merkel cell skin cancer

^ http://www.ebi.ac.uk/efo/EFO_1001471


A carcinoma arising from MERKEL CELLS located in the basal layer of the epidermis and occurring most commonly as a primary neuroendocrine carcinoma of the skin. Merkel cells are tactile cells of neuroectodermal origin and histologically show neurosecretory granules. The skin of the head and neck are a common site of Merkel cell carcinoma, occurring generally in elderly patients. (Holland et al., Cancer Medicine, 3d ed, p1245) [ http://www.ebi.ac.uk/ontology/webulous#OPPL_pattern ]

Synonyms: Merkel Cell Cancer, Merkel Cell Tumor, Merkle Tumors, Merkel Cell Carcinoma