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Leukocyte-Adhesion Deficiency Syndrome

^ http://www.ebi.ac.uk/efo/EFO_1001359


Rare, autosomal recessive disorder caused by deficiency of the beta 2 integrin receptors (RECEPTORS, LEUKOCYTE-ADHESION) comprising the CD11/CD18 family of glycoproteins. The syndrome is characterized by abnormal adhesion-dependent functions, especially defective tissue emigration of neutrophils, leading to recurrent infection. [ http://www.ebi.ac.uk/ontology/webulous#OPPL_pattern ]

Term info

database cross reference
  • MSH:D018370 (http://www.ebi.ac.uk/ontology/webulous#OPPL_pattern)
  • DOID:611 (http://www.ebi.ac.uk/ontology/webulous#OPPL_pattern)
term editor

Sirarat Sarntivijai

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