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capillary leak syndrome

^ http://www.ebi.ac.uk/efo/EFO_1001284


A syndrome characterized by leakage of intravascular fluids into the extravascular space. This syndrome is observed in patients who demonstrate a state of generalized leaky capillaries following shock syndromes, low-flow states, ischemia-reperfusion injuries, toxemias, medications, or poisoning. It can lead to generalized edema and multiple organ failure. [ NCIT:P378 ]

A condition characterized by recurring episodes of fluid leaking from capillaries into extra-vascular compartments causing hematocrit to rise precipitously. If not treated, generalized vascular leak can lead to generalized EDEMA; SHOCK; cardiovascular collapse; and MULTIPLE ORGAN FAILURE. [ http://www.ebi.ac.uk/ontology/webulous#OPPL_pattern ]

Synonyms: capillary hyperpermeability syndrome, SCLS, capillary leak syndrome, AVLS, idiopathic capillary leak syndrome, Capillary leak syndrome (disorder), acute vascular leak syndrome, systemic capillary leak syndrome, CLS, Clarkson disease, Capillary Leak Syndrome

Term info

database cross reference
  • MSH:D019559 (http://www.ebi.ac.uk/ontology/webulous#OPPL_pattern)
  • MedDRA:10007196 (http://www.ebi.ac.uk/ontology/webulous#OPPL_pattern)
  • MESH:D019559 (Orphanet:188)
  • NCIt:C62578 (http://www.ebi.ac.uk/ontology/webulous#OPPL_pattern)
  • Orphanet:188 (MONDO:equivalentTo)
  • DOID:14400 (http://www.ebi.ac.uk/ontology/webulous#OPPL_pattern)
  • MedDRA:10007196 (Orphanet:188)
  • NCIT:C62578 (MONDO:kboom-pr-0.94/0.79/1.45)
  • SCTID:87730004 (MONDO:kboom-pr-1.00/0.92/29.66)
  • UMLS:C0343084 (Orphanet:188)
  • DOID:14400 (MONDO:equivalentTo)
  • SNOMEDCT:87730004 (http://www.ebi.ac.uk/ontology/webulous#OPPL_pattern)
  • GARD:0001084 (Orphanet-shared)
  • ICD10:I78.8 (Orphanet:188)
  • ICD9:448.9 (i2s)
Subsets

ordo_disease

exactMatch

http://linkedlifedata.com/resource/umls/id/C0343084, http://identifiers.org/mesh/D019559, http://identifiers.org/meddra/10007196, http://purl.obolibrary.org/obo/Orphanet_188, http://identifiers.org/snomedct/87730004, http://purl.obolibrary.org/obo/NCIT_C62578, http://purl.obolibrary.org/obo/DOID_14400

has related synonym

periodic systemic capillary leak syndrome, capillary leak syndrome with monoclonal gammopathy

id

EFO:1001284

term editor

Sirarat Sarntivijai