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leukostasis

^ http://www.ebi.ac.uk/efo/EFO_1001016


Abnormal intravascular leukocyte aggregation and clumping often seen in leukemia patients. The brain and lungs are the two most commonly affected organs. This acute syndrome requires aggressive cytoreductive modalities including chemotherapy and/or leukophoresis. It is differentiated from LEUKEMIC INFILTRATION which is a neoplastic process where leukemic cells invade organs. [ http://www.ebi.ac.uk/ontology/webulous#OPPL_pattern ]

A disorder involving the aberrant infiltration and aggregation of leukocytes into the vasculature of the body. Leukostasis is typically detected in the brain and lungs of persons with leukemia. It requires substantial ablative modalities to both reduce the number of cells present and to ensure dispersion of the aggregates. [ NCIT:P378 ]

Synonyms: Leukostasis (morphologic abnormality), leukostasis, Leukostasis, leukostasis (morphologic abnormality)

Term info

database cross reference
  • DOID:12986 (http://www.ebi.ac.uk/ontology/webulous#OPPL_pattern)
  • MESH:D018921 (MONDO:ontobio)
  • DOID:12986 (MONDO:equivalentTo)
  • SNOMEDCT:30419000 (http://www.ebi.ac.uk/ontology/webulous#OPPL_pattern)
  • NCIt:C4062 (http://www.ebi.ac.uk/ontology/webulous#OPPL_pattern)
  • MONDO:0006831
  • MedDRA:10024404 (http://www.ebi.ac.uk/ontology/webulous#OPPL_pattern)
  • UMLS:C0282548 (MONDO:equivalentTo)
  • MSH:D018921 (http://www.ebi.ac.uk/ontology/webulous#OPPL_pattern)
  • MedDRA:10024404 (EFO:1001016)
closeMatch

http://identifiers.org/meddra/10024404, http://identifiers.org/snomedct/30419000

exactMatch

http://linkedlifedata.com/resource/umls/id/C0282548, http://identifiers.org/mesh/D018921, http://purl.obolibrary.org/obo/DOID_12986, http://purl.obolibrary.org/obo/NCIT_C4062

id

EFO:1001016

term editor

Dani Welter

Term relations

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