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endomyocardial fibrosis

^ http://www.ebi.ac.uk/efo/EFO_1000921


A disease characterized by fibrotic thickening of the endocardium, particularly the right and/or left inflow tracts. The disease often involves the atrioventricular valves, leading to valvular regurgitaion. It most commonly occurs in children living within 15 degrees of the equator. [ NCIT:C34585 ]

A condition characterized by the thickening of the ventricular ENDOCARDIUM and subendocardium (MYOCARDIUM), seen mostly in children and young adults in the TROPICAL CLIMATE. The fibrous tissue extends from the apex toward and often involves the HEART VALVES causing restrictive blood flow into the respective ventricles (CARDIOMYOPATHY, RESTRICTIVE). [ http://www.ebi.ac.uk/ontology/webulous#OPPL_pattern ]

Synonyms: Obscure African cardiomyopathy (disorder), Endomyocardial sclerosis, (Becker's disease) or (obscure African cardiomyopathy), Endomyocardial Fibrosis, endomyocardial sclerosis, Becker's disease, African endomyocardial fibrosis, endomyocardial fibrosis, obscure African cardiomyopathy

Term info

database cross reference
  • MedDRA:10014800 (EFO:1000921)
  • GARD:0006340 (MONDO:equivalentTo)
  • MONDO:0006746
  • OMIM:MTHU002869 (http://www.ebi.ac.uk/ontology/webulous#OPPL_pattern)
  • MESH:D004719 (MONDO:ontobio)
  • NCIT:C34585 (exact-label-match)
  • ICD9:425.0 (DOID:12932)
  • DOID:12932 (http://www.ebi.ac.uk/ontology/webulous#OPPL_pattern)
  • DOID:12932 (MONDO:equivalentTo)
  • MedDRA:10014800 (http://www.ebi.ac.uk/ontology/webulous#OPPL_pattern)
  • MSH:D004719 (http://www.ebi.ac.uk/ontology/webulous#OPPL_pattern)
  • COHD:439399 (MONDO:equivalentTo)
  • SNOMEDCT:398716006 (http://www.ebi.ac.uk/ontology/webulous#OPPL_pattern)
  • NCIt:C34585 (http://www.ebi.ac.uk/ontology/webulous#OPPL_pattern)
Subsets

gard_rare

closeMatch

http://identifiers.org/snomedct/111507009, http://identifiers.org/omim/MTHU002869, http://identifiers.org/snomedct/155351008, http://identifiers.org/snomedct/30293000, http://identifiers.org/snomedct/266301006, http://identifiers.org/snomedct/123264005, http://identifiers.org/snomedct/398716006, http://identifiers.org/meddra/10014800, http://linkedlifedata.com/resource/umls/id/C0553980

exactMatch

http://identifiers.org/mesh/D004719, http://purl.obolibrary.org/obo/DOID_12932, http://purl.obolibrary.org/obo/NCIT_C34585

id

EFO:1000921

see also

https://rarediseases.info.nih.gov/diseases/6340/endomyocardial-fibrosis

term editor

Dani Welter

Term relations