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endodermal sinus tumor

^ http://www.ebi.ac.uk/efo/EFO_0007252


A germ cell cancer that has_material_basis_in cells that line the yolk sac of the embryo. [ http://www.ebi.ac.uk/ontology/webulous#OPPL_pattern ]

A non-seminomatous malignant germ cell tumor composed of primitive germ cells. It is the most common malignant germ cell tumor in the pediatric population. It occurs in the infant testis, ovary, sacrococcygeal region, vagina, uterus, prostate, abdomen, liver, retroperitoneum, thorax, and pineal/third ventricle. The tumor mimics the yolk sac of the embryo and produces alpha-fetoprotein (AFP). Treatment includes: surgical resection, radiation, and chemotherapy. This tumor is very responsive to chemotherapy regimens that include cisplatinum. [ NCIT:P378 ]

Synonyms: yolk Sac tumor, yolk Sac tumor site unspecified, yolk Sac tumour site unspecified, endodermal sinus tumor, infantile embryonal carcinoma, Hepatoid yolk sac tumour, yolk sac tumor, yolk SAC tumor, malignant, endodermal sinus neoplasm, Yolk sac tumor (disorder), Endodermal Sinus Tumor, Yolk Sac neoplasm, hepatoid yolk sac tumour, yolk Sac neoplasm

Term info

database cross reference
  • SCTID:404081005 (MONDO:kboom-pr-0.92/0.84/0.08)
  • ONCOTREE:BYST (MONDO:equivalentTo)
  • DOID:1911 (http://www.ebi.ac.uk/ontology/webulous#OPPL_pattern)
  • ICDO:9071/3 (NCIT:C3011)
  • ICD10:C62.9 (Orphanet:876)
  • ICD10:C56 (Orphanet:876)
  • MedDRA:10048251 (Orphanet:876)
  • MSH:D018240 (http://www.ebi.ac.uk/ontology/webulous#OPPL_pattern)
  • UMLS:C0014145 (Orphanet:876)
  • Orphanet:876 (MONDO:equivalentTo)
  • DOID:1911 (MONDO:equivalentTo)
  • MONDO:0005744
  • NCIT:C3011 (MONDO:equivalentTo)
Subsets

ordo_disease

closeMatch

http://identifiers.org/snomedct/74409009, http://identifiers.org/mesh/D018240

exactMatch

http://purl.obolibrary.org/obo/Orphanet_876, http://identifiers.org/snomedct/404081005, http://purl.obolibrary.org/obo/NCIT_C3011, http://identifiers.org/meddra/10048251, http://purl.obolibrary.org/obo/DOID_1911, http://linkedlifedata.com/resource/umls/id/C0014145

has narrow synonym

infantile embryonal carcinoma

id

EFO:0007252

term editor

Sirarat Sarntivijai

Term relations