A transmissible disease that is caused by a protein that is able to induce abnormal folding of normal cellular proteins, leading to characteristic spongiform brain changes, which are associated with neuronal loss without an inflammatory response. Such disorders have typically long incubation periods, but are then generally rapidly progressive and are uniformly fatal. [ NCIT:C128346-modified ]

Synonyms: prion disease prion protein disease spongiform encephalopathy prion induced disorder prion disease pathway

This is just here as a test because I lose it

Term information

database cross reference
  • MESH:D017096 (MONDO:equivalentTo)
  • DOID:649 (MONDO:equivalentTo)
  • KEGG:05020 (MONDO:relatedTo)
  • OMIM:245300
  • ICD9:046.19 (i2s)
  • MedDRA:10079301
  • SCTID:230284004 (MONDO:equivalentTo)
  • MONDO:0005429
  • SNOMEDCT:20484008
  • OMIM:606688
  • ICD10:A81.9 (DOID:649)
  • NCIT:C128346 (MONDO:equivalentTo)
closeMatch

http://purl.obolibrary.org/obo/NCIT_C27585

http://identifiers.org/snomedct/20484008

http://linkedlifedata.com/resource/umls/id/C0162534

http://identifiers.org/snomedct/193172009

comment

Editor note: check relationship to spongiform encephalopathy NCIT:C27585

exactMatch

http://purl.obolibrary.org/obo/DOID_649

http://identifiers.org/snomedct/230284004

http://purl.obolibrary.org/obo/NCIT_C128346

http://identifiers.org/mesh/D017096

gwas trait

true

id

EFO:0004720

term editor

Helen Parkinson

Term relations