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myeloproliferative disorder

^ http://www.ebi.ac.uk/efo/EFO_0004251


Conditions which cause proliferation of hemopoietically active tissue or of tissue which has embryonic hemopoietic potential. They all involve dysregulation of multipotent MYELOID PROGENITOR CELLS, most often caused by a mutation in the JAK2 PROTEIN TYROSINE KINASE.

Synonyms: myeloproliferative neoplasms, Myeloproliferative Neoplasm, myeloproliferative disorders

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