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carcinoid tumor

^ http://www.ebi.ac.uk/efo/EFO_0004243


A usually small, slow-growing neoplasm composed of islands of rounded, oxyphilic, or spindle-shaped cells of medium size, with moderately small vesicular nuclei, and covered by intact mucosa with a yellow cut surface. The tumor can occur anywhere in the gastrointestinal tract (and in the lungs and other sites); approximately 90% arise in the appendix. It is now established that these tumors are of neuroendocrine origin and derive from a primitive stem cell. (From Stedman, 25th ed & Holland et al., Cancer Medicine, 3d ed, p1182). Some carcinoid tumours are a phenotype associated with mutations in the SDHD Gene (evidence OMIM record http://www.omim.org/entry/602690)

Synonyms: ileal carcinoids, ileal carcinoid, carcinoid tumors, intestinal, carcinoid, argentaffinoma

Term info

SNOMEDCT definition citation

SNOMEDCT:81622000, SNOMEDCT:443492008

gwas trait

true

term editor

Dani Welter

Term relations

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