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obstructive sleep apnea

^ http://www.ebi.ac.uk/efo/EFO_0003918


A disorder characterized by recurrent episodic disruptions of breathing during sleep. It is caused by the intermittent relaxation of pharyngeal muscles leading to the narrowing or complete blockage of the upper airway. This results in compensatory arousal from sleep to breathe again. An anatomically narrow airway from body habitus or enlarged pharyngeal structures may also predispose to obstruction. Clinical presentation usually includes snoring, daytime sleepiness, difficulty concentrating and fatigue. Clinical course may progress to chronic hypoxemia with cardiovascular and cerebrovascular sequelae.

A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395)

Synonyms: Sleep Apnea, Obstructive, Obstructive Sleep Apneas, Syndrome, Upper Airway Resistance, Sleep Apnea, Obstructive Sleep Apnea Syndrome, Syndrome, Sleep Apnea, Obstructive, Apnea, Obstructive Sleep, Syndrome, Obstructive Sleep Apnea, Sleep Apneas, Obstructive, Apneas, Obstructive Sleep, Sleep Apnea Syndrome, Obstructive, Upper Airway Resistance Sleep Apnea Syndrome

Term info

NCI Thesaurus definition citation

NCIT:C27168, NCIt:C116337

SNOMEDCT definition citation

SNOMEDCT:78275009

bioportal provenance

Upper Airway Resistance Sleep Apnea Syndrome[accessedResource: MSH:D020181][accessDate: 05-04-2011], A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395)[accessedResource: MSH:D020181][accessDate: 05-04-2011], Apnea, Obstructive Sleep[accessedResource: MSH:D020181][accessDate: 05-04-2011], Syndrome, Sleep Apnea, Obstructive[accessedResource: MSH:D020181][accessDate: 05-04-2011], Sleep Apnea Syndrome, Obstructive[accessedResource: MSH:D020181][accessDate: 05-04-2011], Apneas, Obstructive Sleep[accessedResource: MSH:D020181][accessDate: 05-04-2011], Syndrome, Upper Airway Resistance, Sleep Apnea[accessedResource: MSH:D020181][accessDate: 05-04-2011], Obstructive Sleep Apnea Syndrome[accessedResource: MSH:D020181][accessDate: 05-04-2011], Sleep Apneas, Obstructive[accessedResource: MSH:D020181][accessDate: 05-04-2011], Sleep Apnea, Obstructive[accessedResource: MSH:D020181][accessDate: 05-04-2011], Syndrome, Obstructive Sleep Apnea[accessedResource: MSH:D020181][accessDate: 05-04-2011], Obstructive Sleep Apneas[accessedResource: MSH:D020181][accessDate: 05-04-2011]

gwas trait

true

term editor

Tomasz Adamusiak

Term relations

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