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systemic lupus erythematosus

^ http://www.ebi.ac.uk/efo/EFO_0002690


A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.

Synonyms: Lupus Erythematosus, Systemic, Disease, Libman-Sacks, Libman Sacks Disease, LIBMAN SACKS DIS, Libman-Sacks Disease, SLE, lupus, Lupus Erythematosus Disseminatus

Term info

OMIM definition citation

OMIM:152700, OMIM:612253, OMIM:610927, OMIM:605218, OMIM:601744, OMIM:612251, OMIM:609939

SNOMEDCT definition citation

SNOMEDCT:55464009

bioportal provenance

A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.[accessedResource: MSH:D008180][accessDate: 05-04-2011], SLE[accessedResource: MSH:D008180][accessDate: 05-04-2011], Libman-Sacks Disease[accessedResource: MSH:D008180][accessDate: 05-04-2011], Libman Sacks Disease[accessedResource: MSH:D008180][accessDate: 05-04-2011], Lupus Erythematosus Disseminatus[accessedResource: MSH:D008180][accessDate: 05-04-2011], Disease, Libman-Sacks[accessedResource: MSH:D008180][accessDate: 05-04-2011], LIBMAN SACKS DIS[accessedResource: MSH:D008180][accessDate: 05-04-2011], Lupus Erythematosus, Systemic[accessedResource: MSH:D008180][accessDate: 05-04-2011]

definition citation

systemic lupus erythematosus

gwas trait

true

term editor

Tomasz Adamusiak