A progressive degenerative disorder of the central nervous system characterized by loss of dopamine producing neurons in the substantia nigra and the presence of Lewy bodies in the substantia nigra and locus coeruleus. Signs and symptoms include tremor which is most pronounced during rest, muscle rigidity, slowing of the voluntary movements, a tendency to fall back, and a mask-like facial expression. [ ]

Synonyms: Parkinson's syndrome Parkinsons Parkinson's disease Primary Parkinsonism Parkinsons disease Parkinson disease Parkinson's disease (disorder) Parkinson's disease NOS Parkinson Disease, Idiopathic PARKINSON DIS Paralysis agitans IDIOPATHIC PARKINSONS DIS PARKINSON DIS IDIOPATHIC Parkinsonism, Primary IDIOPATHIC PARKINSON DIS Parkinson's Disease, Lewy Body Idiopathic PD Idiopathic Parkinson Disease Lewy Body Parkinson's Disease LEWY BODY PARKINSON DIS Parkinsonian disorder Parkinson's Idiopathic Parkinson's Disease Parkinson's disease NOS (disorder) paralysis agitans Lewy Body Parkinson Disease PARKINSONS DIS IDIOPATHIC PARKINSONS DIS Parkinson's Disease, Idiopathic Parkinson syndrome PARKINSONS DIS LEWY BODY

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Term information

database cross reference
closeMatch

http://identifiers.org/snomedct/155002003

exactMatch

http://purl.obolibrary.org/obo/DOID_14330

gwas trait

true

id

EFO:0002508

term editor

Ele Holloway