JSON

multiple myeloma

^ http://www.ebi.ac.uk/efo/EFO_0001378


A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.

A bone marrow-based plasma cell neoplasm characterized by a serum monoclonal protein and skeletal destruction with osteolytic lesions, pathological fractures, bone pain, hypercalcemia, and anemia. Clinical variants include non-secretory myeloma, smoldering myeloma, indolent myeloma, and plasma cell leukemia. (WHO, 2001)

A myeloma that is located_in the plasma cells in bone marrow.

Synonyms: Plasma-Cell Myelomas, Plasmacytic myeloma, Multiple myeloma, no ICD-O subtype, Myelomas, Plasma-Cell, MULT MYE W/O ACHV RMSON, Myeloma, NOS, Myeloma, Plasma Cell, Cell Myelomas, Plasma, Myeloma, Multiple myeloma (disorder), Kahler's disease, Multiple myeloma without mention of having achieved remission, Plasma Cell Myelomas, Myeloma, Multiple, Myelomas, Plasma Cell, Myeloma Multiple, Myeloma-Multiples, Myeloma-Multiple, Cell Myeloma, Plasma, Multiple myeloma without mention of remission, Disease, Kahler, Multiple myeloma, morphology (morphologic abnormality), Multiple Myelomas, Myeloma, Plasma-Cell, Plasma Cell Myeloma, [M]Plasma cell myeloma, Myelomas, Multiple, Myelomatoses, Myelomatosis, Multiple myeloma (clinical), MULT MYELM W/O REMISSION, Plasma-Cell Myeloma, Kahler disease, Multiple myeloma, no ICD-O subtype (morphologic abnormality)

Term info

SNOMEDCT definition citation

SNOMEDCT:55921005, SNOMEDCT:109989006

bioportal provenance

Myeloma, Multiple[accessedResource: MSH:D009101][accessDate: 05-04-2011], Kahler's disease[accessedResource: SNOMEDCT:109989006][accessDate: 05-04-2011], Myelomatoses[accessedResource: MSH:D009101][accessDate: 05-04-2011], Plasma Cell Myeloma[accessedResource: NCIt:C3242][accessDate: 05-04-2011], Myelomatosis[accessedResource: SNOMEDCT:109989006][accessDate: 05-04-2011], A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.[accessedResource: MSH:D009101][accessDate: 05-04-2011], Myeloma, Plasma-Cell[accessedResource: MSH:D009101][accessDate: 05-04-2011], Myelomas, Multiple[accessedResource: MSH:D009101][accessDate: 05-04-2011], Kahler disease[accessedResource: NCIt:C3242][accessDate: 05-04-2011], Plasma Cell Myelomas[accessedResource: MSH:D009101][accessDate: 05-04-2011], Multiple myeloma, morphology (morphologic abnormality)[accessedResource: SNOMEDCT:55921005][accessDate: 05-04-2011], Multiple myeloma without mention of having achieved remission[accessedResource: ICD9:203.00][accessDate: 05-04-2011], Myeloma-Multiples[accessedResource: MSH:D009101][accessDate: 05-04-2011], Multiple Myelomas[accessedResource: MSH:D009101][accessDate: 05-04-2011], MULT MYE W/O ACHV RMSON[accessedResource: ICD9:203.00][accessDate: 05-04-2011], Multiple myeloma (clinical)[accessedResource: SNOMEDCT:109989006][accessDate: 05-04-2011], Myeloma Multiple[accessedResource: MSH:D009101][accessDate: 05-04-2011], Myeloma[accessedResource: SNOMEDCT:55921005][accessDate: 05-04-2011], Plasma-Cell Myelomas[accessedResource: MSH:D009101][accessDate: 05-04-2011], Myeloma-Multiple[accessedResource: MSH:D009101][accessDate: 05-04-2011], Plasmacytic myeloma[accessedResource: SNOMEDCT:109989006][accessDate: 05-04-2011], Cell Myeloma, Plasma[accessedResource: MSH:D009101][accessDate: 05-04-2011], Multiple myeloma, no ICD-O subtype (morphologic abnormality)[accessedResource: SNOMEDCT:55921005][accessDate: 05-04-2011], Multiple myeloma (disorder)[accessedResource: SNOMEDCT:109989006][accessDate: 05-04-2011], [M]Plasma cell myeloma[accessedResource: SNOMEDCT:55921005][accessDate: 05-04-2011], Myeloma, NOS[accessedResource: SNOMEDCT:55921005][accessDate: 05-04-2011], Multiple myeloma, no ICD-O subtype[accessedResource: SNOMEDCT:55921005][accessDate: 05-04-2011], A myeloma that is located_in the plasma cells in bone marrow.[accessedResource: DOID:9538][accessDate: 05-04-2011], Plasma-Cell Myeloma[accessedResource: MSH:D009101][accessDate: 05-04-2011], Disease, Kahler[accessedResource: MSH:D009101][accessDate: 05-04-2011], Myelomas, Plasma-Cell[accessedResource: MSH:D009101][accessDate: 05-04-2011], Myeloma, Plasma Cell[accessedResource: MSH:D009101][accessDate: 05-04-2011], Cell Myelomas, Plasma[accessedResource: MSH:D009101][accessDate: 05-04-2011], Myelomas, Plasma Cell[accessedResource: MSH:D009101][accessDate: 05-04-2011], A bone marrow-based plasma cell neoplasm characterized by a serum monoclonal protein and skeletal destruction with osteolytic lesions, pathological fractures, bone pain, hypercalcemia, and anemia. Clinical variants include non-secretory myeloma, smoldering myeloma, indolent myeloma, and plasma cell leukemia. (WHO, 2001)[accessedResource: NCIt:C3242][accessDate: 05-04-2011]

term editor

James Malone, Tomasz Adamusiak